The Position

2025 Summer Intern – Neuroscience – Translational Neuroscience

Department Summary

The Neuroscience department is focused on studying the biology of neurodegenerative diseases and translating these findings into therapeutics for the treatment of neurological disorders. The Translational Neuroscience group provides in vivo support for drug development. We characterize mouse models of neurodegenerative disease including Alzheimer’s, Parkinson’s disease and ALS. We are seeking a talented and highly motivated summer intern to join our lab investigate the effects of TAR DNA binding protein 43 (TDP43) deletion on cellular homeostasis (RNA spicing), neuroinflammation, and development of motor deficits in this mouse model of ALS. 

This internship position is located in South San Francisco.  

The Opportunity

Characterize disease pathology in different TDP43 mouse models of ALS.Section brain tissue, isolate protein/RNA from mouse brain tissuePerform immunohistochemical or immunofluorescence staining of brain tissue followed by microscopy.  Perform Western blots or qPCR.Perform behavioral assays to monitor motor coordination, muscle strength, and muscle compound action potential (CMAP).

Program Highlights

Intensive 12-weeks, full time (40 hours per week) paid internship.Program start dates are in May and June 2023.Experience and learn how research is performed in an industry setting.Opportunity to present project work to senior leaders.Lead or participate in intern committees to design and coordinate program events and initiatives.Professional & personal development curriculum throughout the program, including networking opportunities, workshops, and panel discussions.Participate in volunteer projects, social events, and team-building activities.

Who You Are

Must be pursuing a Bachelor's degreeMust have attained a  Bachelor's degree (recent graduates not currently enrolled in a grad program)Must be pursuing a Master's degreeMust have attained a Master's degreeMust be pursuing a PhDMust have attained a PhD

Preferred majors:

Neuroscience, Molecular Cell Biology, Biochemistry, Immunology

Required Skills:

Experienced working “at the bench”Understands and performs immunohistochemistry (IHC)Experience with florescent microscopyIn vivo experience handling animals a plusFast learner

Preferred Knowledge, Skills, and Qualifications

Excellent communication, collaboration, and interpersonal skills.Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.Excellent record keepingCan work independently

 

Relocation benefits are not available for this job posting. 

The expected salary range for this position based on the primary location of  California is $25-$45 hour.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits. 

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