Job Description

The Cell Pharmacology group in the Department of Quantitative Biosciences is seeking a highly motivated Scientist with a background in immunology, oncology or cardiometabolic cellular assays to join our research laboratories in Boston. The primary tasks of the successful candidate will be to develop and characterize high throughput in vitro and ex vivo cell-based assays to support autoimmune, cancer, or cardiometabolic projects. These high throughput cell assays will use cell lines, primary human cells and human organoids.

Responsibilities:

Establish and characterize ex vivo translational models, including tumoroids and co-culture systems. Develop and optimize assays at scale to support potential compound screening, biomarker identification and mechanism of action studies.

Characterize and optimize in vitro assays at scale to support potential compound screening, biomarker identification and mechanism of action studies.

Evaluate the pharmacology of novel molecules, peptides, antibodies and other modalities for therapeutic potential in immunology, oncology or cardiometabolic indications.

Work with both internal and external stakeholders and manage cell reagent sourcing activities.

Maintain timely, accurate laboratory records of activities & comply with good documentation practices.

Effectively partner with integrated teams in a matrix organizational setting to contribute to the conduct of studies and to the success of discovery programs.

Required Education & Experience:

B.S./B.A. degree with a minimum 3 years of full-time relevant work experience; or a M.S. degree with a minimum 1 year of full-time relevant work experience.

Proficient in maintenance and troubleshoot of in vitro and ex vivo or translational or tumoroid models.

Experiences with basic molecular biology techniques including PCR, qPCR, dPCR, Western blot, ELISA.

Candidate should be a strong team player with excellent oral and written communication skills.

Preferred Experience:

Prior experience with primary human cells and ex vivo translational models

Experience in the selection, optimization and characterization of effective immunology, oncology, or cardiometabolic assays

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If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

Yes

Travel Requirements:

No Travel Required

Flexible Work Arrangements:

Not Applicable

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

BSL2, OEB4, OEB5

Job Posting End Date:

11/1/2024

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R318158