Exciting leadership opportunity! The Jackson Laboratory (JAX) is hiring an Associate Director of Single Cell Biology Lab, a core facility driving innovative single cell and spatial omics technologies. Join our efforts to provide cutting-edge molecular assays, multiplex imaging, and organoid screening platforms to researchers across JAX and UConn campuses.  The Associate Director will oversee a dynamic, multidisciplinary team of scientists that provides world class service and advanced groundbreaking research across multiple campuses.

If you hold a PhD in a biomedical field with 8+ years of experience in single cell & spatial profiling techniques, excel at developing and implementing innovative technologies, and are passionate about collaborative, impactful research, we’d love to hear from you!  This is your chance to make an impact and drive the future of single cell & spatial biology at JAX!

Join us and lead transformative science in a world-class environment!

The incumbent will support the Director, Single Cell Biology with on-going R&D and operations of the Single Cell Biology Laboratory (SCBL) within the Scientific Services at JAX supporting all JAX campuses. This is one of two Associate Director positions within the SCBL, with this position focused on dry lab aspects and the other on wet lab aspects of the service. Service offerings within SCBL include single cell molecular assays, imaging-based multiplex assays, and functional cell biology assays inclusive of an organoid screening platform. The Associate Directors will assist in the establishment and maintenance of these state-of-the art methods in this biological space and the delivery of these methods and services in support of the JAX research community and its external partners. This Associate Director position will have key responsibilities in directly interacting with end users in the design and execution of studies, in establishing and maintaining laboratory informatics, data management, robotics and computer infrastructure, single cell and imaging analytics, and the coordination with Computational Sciences Scientific Services in this analytics.  

Key Responsibilities:

Assists in the delivery of integrated single cell biology operations supporting all three JAX campuses needsAssists in the delivery of integrated single cell biology operations supporting all University of Connecticut campusesEvaluate, test, and develop analytics capabilities relevant to single cell, multiplex imaging, and organoid screening technologiesDirect management of analytics/bioinformatics staff (currently 2 FTE) within the SCBLImplementation and management of a Laboratory Information Management System (LIMS) for SCBLOversight of robotics programming and the computer infrastructure of the SCBL, and the associated integration of data collection from SCBL equipmentCollaboration with members of Computational Sciences Scientific Services to ensure appropriate computational expertise is established/maintained for emerging and current data types generated by the SCBLCoordination with members of Computational Sciences Scientific Services to ensure SCBL end user computational needs are anticipated and fulfilledThrough the NCI P30 Basic Cancer Center grant, ensures the successful implementation of single cell, multiplex imaging, and organoid screening analytics capabilities into JAX Cancer Center member research programsProvide consultative services and project management for experimental design, data acquisition, analysis and downstream interpretationInterfaces with JAX Genomics Technology core to facilitate SCBL’s extensive use of sequencingInterfaces with JAX Microscopy core to coordinate efforts on imaging analysis workflows and data managementAssures JAX (research, clinical clients and collaborators) has access to the highest-quality and cost effective SCBL services and evolves operational approaches to meet this requirement (including outsourcing)Extend the JAX platform access through collaborative, service and commercial partnershipsDependent on external grant support, either secured by the SCBL Director, or the Associate Director themselves, the position will allow up to 50% effort towards research. This is fully dependent on all the service-related duties being successfully fulfilled.Research must be relevant to advancing and/or applying single cell technologies to JAX research interests in human and/or mouse systems (e.g. regenerative biology, women’s health, cancer biology, neurobiology, aging);Publishes peer reviewed articles and presents at domestic and international scientific conferencesHelps to achieve appropriate JAX-SCBL Operations overall goal as measured by:Builds reputation as a thought and application leader and for delivery of a superior offeringSuccessful implementation of data management infrastructureDelivers data at or below an acceptable deviation frequencySuccessful integration of computational and analytics capabilities with Computational Sciences Scientific ServiceSuccessful involvement (as lead PI or Key Personnel) on internal and/or external grant applicationsSuccessful publication in peer reviewed articles and/scientific papers. First author, corresponding author, and co-authorships are all signs of success.JAX is recognized as a leader in Single Cell Biology with an established academic reputationJAX becomes a preferred provider of external servicesJAX grows its IP portfolioJAX realizes surplus and research reinvestment from JAX-SCBL operations

Minimum Qualifications:

PhD in relevant field (e.g. Physics, Mathematics, Computer Sciences, Genomics or similar)Demonstrated experience (3+ years) in single cell analytics inclusive of single cell RNA-seq, ATAC-seq, spatial transcriptomics, and/or highly multiplexed imagingDemonstrated experience in bioinformatics, machine learning, and/or high performance computingDemonstrated collaborative effectivenessExcellent verbal and written communication skills

Pay Range: $119,533 - $155,393

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About JAX:

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org​​​​​​​.

EEO Statement:

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.