Associate Principal Scientist - Process Analytical Technology (PAT)

Location: Mt. Vernon, IN or Durham, NC

Introduction to Role:

Are you ready to make an outstanding impact in the world of science? We have an exciting opportunity for you to join our dynamic and enthusiastic team at AstraZeneca, where we turn ideas into life-changing medicines. We are looking for an Associate Principal Scientist - Process Analytical Technology (PAT) to join our Technical Operations, Science and Innovation (TOSI) team. This role is pivotal in supporting the transformation of AZ commercial manufacturing through continuous direct compression (CDC) for oral solid dosage forms (OSDs).

Accountabilities:

As an Associate Principal Scientist, you will provide expert support to continuous manufacturing of commercial products. Your knowledge in PAT, analytical science and technologies will be crucial in ensuring efficient and effective support to internal and external manufacturing sites and testing laboratories located in multiple countries. You will also play a proactive role in seeing opportunities for PAT method improvements and provide technical leadership to Issue Management Team (IMT).

Essential Skills/Experience:

Ph.D. – 3+ years, MS – 5+ years, BS – 8+ years of relevant industry experience. Degree in relevant field (Analytical Chemistry, Pharmaceutical Sciences, or Engineering etc.)Scientific leadership skillsProven track record to think and operate across functional boundariesEffective influencing and prioritization skillsGood communication and stakeholder management skillsA strong understanding of key process analytical technologies, especially NIR, Raman and microwave resonance spectroscopyDemonstrated expertise in PAT method development, implementation, optimization and use of Multi-variate data analysis/ Chemometrics (MVDA, PCA, PLS)Knowledge of the principles and management of Safety, Health & Environment (SHE)Business acumen and capability to understand business cases in subject matter areas.

Desired Skills/Experience:

Work experience in the Pharmaceutical industry in a PAT based roleExperience in or exposure to multiple subject areas in CMC and related functionsAn understanding of other key analytical techniques such as separation science, NMR and mass spectrometryPrevious experience and training in Lean, problem-solving tools and experience in data analysis and interpretation

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, we are driven by our commitment to deliver accelerated growth and to make people's lives better. We are leading the way in delivering Lean processes that drive greater efficiency and speed. Sustainable practices are at the heart of what we do, ensuring we manage our environmental impact across all our activities and products. We strive to build a high-performing network that values both efficient execution and a collaborative team environment.

Are you ready to make a positive impact on society through our sustainability goals? Join us now and be a key contributor to Zero Carbon by 2025 and carbon negative across the entire value chain by 2030. Everyone can contribute towards our collective legacy of doing good for people, the environment and society.

Apply now to be part of our journey!

Date Posted

09-Oct-2024

Closing Date

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.