Site Name: USA - Pennsylvania - Upper Providence Posted Date: Dec 20 2024 We are currently looking for highly motivated, entry-level organic chemist to join our Medicinal Chemistry team in suburban Philadelphia. Our department partners with program teams across GSK’s research units to deliver high quality small molecules, from hit generation through late-stage lead optimization to address increasingly complex disease areas. The purpose of the role is to provide a high level of scientific and technical contributions to projects within the Medicinal Chemistry portfolio (including but not limited to: small molecules, PROTACs, degraders, oligonucleotides, covalents, and antibody-drug conjugates) with a primary responsibility of driving efficiencies, applying novel synthetic methods and techniques to design, synthesize, and purify candidate molecules. The successful applicant will become fluent in all areas of medicinal chemistry while working as part of a highly productive team to design and synthesize developable drug molecules. The role involves, to differing degrees, medicinal chemistry, data analytics, designing compounds to test medicinal chemistry hypotheses, synthetic organic chemistry to support both medicinal chemistry and/or candidate selection and championing technological advances. The successful candidate will work collaboratively across teams of synthetic chemists, analytical chemists, and data analytics experts to help invent these new processes and chemistries to solve impactful problems that will accelerate delivery of important medicinal advancements to patients. Successful candidates must be able to think creatively, champion the needs of the organization and work collaboratively within a team environment.  This role will provide you the opportunity to lead key activities to progress your career.  These responsibilities include some of the following: Apply modern synthetic technologies to the preparation of structurally complex organic molecules by performing multi-step organic synthesis to prepare intermediates and final products, from milligram to multigram reaction scale Use and operate analytical instrumentation for the analysis and characterization of organic compounds (NMR/LCMS/HPLC) Maintain accurate and detailed laboratory records using Electronic Notebook Analyzes and interprets experimental data with the ability to optimize and troubleshoot chemical reactions Proactively seek peer feedback of own work to improve the probability of success and time efficiency of their scientific strategies Work effectively in both independent and highly collaborative, multi-functional teams to drive projects forward Prepare summaries of research results and communicate findings to team members through written reports and oral presentations Stay current with developments in the field of synthetic organic chemistry, medicinal chemistry, and drug discovery through literature review Write-up experimental procedures for journal and patent applications to secure GSK’s intellectual property Act in accordance with all GSK policies on personnel, safety/health/environment regulations, best laboratory practice, and Code of Conduct Why you? Basic Qualifications: Bachelor’s degree in Chemistry, Chemical Biology, or Biochemistry degree Evidence of working in an organic/synthetic chemistry lab Preferred Qualifications: Bachelor or Master’s degree in Chemistry, Chemical Biology, or Biochemistry with some industry experience, and a significant organic chemistry component Proven track record of lab-based synthetic organic chemistry experience Technically sound in organic chemistry fundamentals: strong understanding of reactions, mechanisms, and reactivity Proficient in searching the chemical literature to evaluate potential solutions to synthetic challenges Strong problem solving abilities, including critical thinking skills and attention to detail Excellent interpersonal and communication skills Experience in synthetic chemistry; the application of new synthetic methodology and execution of multi-step syntheses Peer-reviewed publications, patents, or presentations #LI-GSK Why GSK? Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: Operating at pace and agile decision-making – using evidence and applying judgement to balance pace, rigour and risk. Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution. Continuously looking for opportunities to learn, build skills and share learning. Sustaining energy and well-being Building strong relationships and collaboration, honest and open conversations. Budgeting and cost-consciousness Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. 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