Chemist (RNA Synthesis) - Indianapolis, IN
Bureau Vertias North America
Job Description
Overview:
Position Title: Analyst I
Business Title: Chemist – RNA Synthesis
Department: ATL
Location: Indianapolis, IN
Reports to: Manager
FLSA: Non-Exempt
Hours Worked: Monday through Friday, forty hours per week.
However, must be flexible to meet the needs of the department and complete other projects as assigned.
Position Summary:
The Chemist is responsible for the synthesis and downstream processing of oligo synthesis using various analytical techniques. AKTA, LC-MS, UPLC, LTQ, QDA analytical instruments are used.
Duties and Responsibilities:
Downstream processing of synthetic compounds (purification and buffer exchange) Carefully prepare laboratory samples from stock/inventory for biological testing Maintain accurate and careful records Organize inventory of samples Synthesis of oligonucleotides on AKTA oligo pilot for solid-phase oligonucleotide synthesis Downstream processing of processing of synthetic compounds (purification and buffer exchange) Carefully prepare laboratory samples from stock/inventory for biological testing Use of general laboratory equipment including but not limited to pipettors, centrifuges, incubators, biological safety cabinets and balances Instrumentation for methods and techniques described may include AKTA, LC-MS, UPLC, LTQ, QDA, Nanodrop, etc. Data analysis and troubleshooting Lab experience with solution preparation, separation, quantification, synthesis methodologies for DNA/RNA, proteins, oligonucleotides, etc. Software includes instrument-specific for capturing and analyzing data, Microsoft Office (Word, Excel, PowerPoint, Outlook, Teams/Sharepoint, etc), LIMS, electronic laboratory notebooks, etc. Detailed record keeping of daily experiments in ELNs General Lab Maintenance Follow the guidelines set forth with clients and Company Quality, Health, Safety, Security and Environmental policies and procedures. Comply with clients’ and Company management systems in accordance with appropriate regulatory agencies. Perform other essential tasks projects and responsibilities as required. Other duties as defined by Manager, department needs and workload
Skills & Proficiencies:
Demonstrated productivity in chemical or biological laboratory setting Experience reading and understanding scientific data Familiarity with scientific instruments and laboratory techniques Experience with RNA handling or isolation Experience with nucleotide, nucleoside or oligonucleotide synthesis Familiar with dilution and concentration calculations Strong organizational skills Strong written and oral communication skills Confident, execution-focused, and team oriented with a desire to thrive in a fast-paced growing environment Written and verbal communication skills including the ability to communicate effectively in a group setting, with colleagues and clients Ability to perform multiple tasks Ability to organize and prioritize workload to meet or exceed deadlines Individual and Team work ethic Proficiency with Windows, Word & Excel Attention to detail Positive attitude, self-motivated, high level of engagement Adheres to company values
Education and Experience:
Degree requirement: Bachelor's Degree in Chemistry, Biochemistry, or closely related field Minimum of one (1) year of experience in a chemistry/biology lab setting
An equivalent combination of education and experience may be accepted in lieu of above.
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