Spring House, Pennsylvania, US
1 day ago
Director, DSDH, Discovery and Portfolio Strategy

Johnson and Johnson Innovative Medicine RD is recruiting for a Director, DSDH, Discovery and Portfolio Strategy, Immunology. This outstanding leader and data science expert will work to optimize our discovery and development portfolios with a focus on translation of genomics, transcriptomics, proteomics, and metabolomics data to inform target identification and validation, as well as biomarker discovery.

This role requires knowledge of sophisticated analytics of multivariate data domains, and utilizing artificial intelligence and machine learning techniques to optimize programs across discovery and development. This includes novel uses of multi-omic and clinical data from multiple sources, including, but not limited to: large biobanks; preclinical and clinical studies; and real-world data. Analyses will drive precision medicine strategy for target discovery and patient stratification. This role will also support integrating data science and digital health throughout development programs across the portfolio. This role will report to the Vice President, DSDH, Immunology, Cardiopulmonary, and Communicable Diseases.

Key Responsibilities:

The ideal candidate will have a strong understanding of disease biology and AI/ML techniques and their application in biomarker and drug discovery, as well as experience with inflammatory diseases. The candidate should have strong stakeholder management skills, and will be responsible for ideating and executing the strategy of AI and ML-based target and biomarker discovery for the Data Science and Digital Health team that is aligned to immunology, all in close partnership with internal stakeholders and partners.

The candidate's work will be tightly coupled with our Immunology Discovery and Translational Science Medicine, Population Genetics, and RD Data Science teams.

Create the strategy and process for evaluating target opportunities from the perspective of multi-omics biology, drawing upon a combination of internal and external resources.Develop tools and platforms to enable AI/ML-driven discovery and translational science initiatives.Collaborate with scientists and clinicians to develop data-driven strategies for precision medicine in immunology by being forward-looking and foreseeing the path to launch.Chart the path for the use of real-world data integrated within clinical programs to accelerate development, and strengthen understanding of unmet need and opportunities to benefit patient subtypes within and across immunology indications.Manage a robust portfolio of Data Science projects spanning RWE to Computer Vision to Digital Health from a milestone perspective

Remain current on the constantly evolving landscape of Immunology, genomics, bioinformatics and AI/ML research and the use of RWD in search of new strategies for strengthening the portfolio.

Johnson and Johnson Innovative Medicine RD is recruiting for a Director, DSDH, Discovery and Portfolio Strategy, Immunology. This outstanding leader and data science expert will work to optimize our discovery and development portfolios with a focus on translation of genomics, transcriptomics, proteomics, and metabolomics data to inform target identification and validation, as well as biomarker discovery.

This role requires knowledge of sophisticated analytics of multivariate data domains, and utilizing artificial intelligence and machine learning techniques to optimize programs across discovery and development. This includes novel uses of multi-omic and clinical data from multiple sources, including, but not limited to: large biobanks; preclinical and clinical studies; and real-world data. Analyses will drive precision medicine strategy for target discovery and patient stratification. This role will also support integrating data science and digital health throughout development programs across the portfolio. This role will report to the Vice President, DSDH, Immunology, Cardiopulmonary, and Communicable Diseases.

Key Responsibilities:

The ideal candidate will have a strong understanding of disease biology and AI/ML techniques and their application in biomarker and drug discovery, as well as experience with inflammatory diseases. The candidate should have strong stakeholder management skills, and will be responsible for ideating and executing the strategy of AI and ML-based target and biomarker discovery for the Data Science and Digital Health team that is aligned to immunology, all in close partnership with internal stakeholders and partners.

The candidate's work will be tightly coupled with our Immunology Discovery and Translational Science Medicine, Population Genetics, and RD Data Science teams.

Create the strategy and process for evaluating target opportunities from the perspective of multi-omics biology, drawing upon a combination of internal and external resources.Develop tools and platforms to enable AI/ML-driven discovery and translational science initiatives.Collaborate with scientists and clinicians to develop data-driven strategies for precision medicine in immunology by being forward-looking and foreseeing the path to launch.Chart the path for the use of real-world data integrated within clinical programs to accelerate development, and strengthen understanding of unmet need and opportunities to benefit patient subtypes within and across immunology indications.Manage a robust portfolio of Data Science projects spanning RWE to Computer Vision to Digital Health from a milestone perspective

Remain current on the constantly evolving landscape of Immunology, genomics, bioinformatics and AI/ML research and the use of RWD in search of new strategies for strengthening the portfolio.

PhD or MD with 5 years of progressive experience or MS with 7 years of progressive experienceBiologic or computational science, or other related quantitative field (e.g., biomedical engineering, computational biology, genetics), and applying data science to drug discovery and development.Ability to translate data into easily digestible information and imputing strategies into executable action plans.Experience with deriving insights from high-dimensional molecular, imaging, or real-world data.Prior experience working in the context of target discovery and validation or biomarkers in healthcare setting.Strong project management skills to prioritise projects across a complex portfolioExperience working in matrix organizations and leading interdisciplinary teams including scientists, clinicians, business, and finance.Collaboratative nature to work with DSDH and IMM TA leadership team to identify key areas where data science can deliver significant business value and innovation, ensure scientific impact and alignment between DSDH and IMM TA goals objectivesAbility to clearly communicate technical work to a diverse audience is required.Play a leadership role in the JJ IM RD data science community.Ability to travel both domestic and international on an as-needed basis (up to 10% yearly)

The anticipated base pay range for this position is $146,000 to $251,850. California Bay Area - The anticipated base pay range for this position is $167,000 to $289,800.

The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis.

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).This position is eligible to participate in the Company’s long-term incentive program.Employees are eligible for the following time off benefits:Vacation – up to 120 hours per calendar yearSick time - up to 40 hours per calendar year; for employees who reside in the State of Washington – up to 56 hours per calendar yearHoliday pay, including Floating Holidays – up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar yearAdditional information can be found through the link below. https://www.careers.jnj.com/employee-benefits

The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market."

Johnson Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

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PhD or MD with 5 years of progressive experience or MS with 7 years of progressive experienceBiologic or computational science, or other related quantitative field (e.g., biomedical engineering, computational biology, genetics), and applying data science to drug discovery and development.Ability to translate data into easily digestible information and imputing strategies into executable action plans.Experience with deriving insights from high-dimensional molecular, imaging, or real-world data.Prior experience working in the context of target discovery and validation or biomarkers in healthcare setting.Strong project management skills to prioritise projects across a complex portfolioExperience working in matrix organizations and leading interdisciplinary teams including scientists, clinicians, business, and finance.Collaboratative nature to work with DSDH and IMM TA leadership team to identify key areas where data science can deliver significant business value and innovation, ensure scientific impact and alignment between DSDH and IMM TA goals objectivesAbility to clearly communicate technical work to a diverse audience is required.Play a leadership role in the JJ IM RD data science community.Ability to travel both domestic and international on an as-needed basis (up to 10% yearly)

The anticipated base pay range for this position is $146,000 to $251,850. California Bay Area - The anticipated base pay range for this position is $167,000 to $289,800.

The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis.

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).This position is eligible to participate in the Company’s long-term incentive program.Employees are eligible for the following time off benefits:Vacation – up to 120 hours per calendar yearSick time - up to 40 hours per calendar year; for employees who reside in the State of Washington – up to 56 hours per calendar yearHoliday pay, including Floating Holidays – up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar yearAdditional information can be found through the link below. https://www.careers.jnj.com/employee-benefits

The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market."

Johnson Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

#LI-GR1

#JRDDS

#JNJDataScience

#LI-Hybrid

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