**Responsibilities** The Mayo Clinic Department of Neuroscience is recruiting an outstanding mid-career scientist (PhD, MD/PhD, MD or equivalent) with strong training, expertise and experience in neuroimmunology and applies these to the knowledge, diagnosis and treatment of neurodegenerative and other aging-related neurological disorders. The ideal candidate is expected to have a history of extramural funding, high impact publications, as well as a proven record of collaborative team science endeavors. The ideal candidate will have a track record of discovery and application of basic science approaches including but not limited to model systems such as animal or human stem cell based models, cell biology, and/or genetic engineering to uncover neuroimmunological basis of disease and treatment thereof. They will be expected to develop and apply these tools for generating therapeutic applications in collaboration with other investigators and taking advantage of the innovative, translational environment at Mayo Clinic. The selected candidate will establish a robust Research Program with a focus on the Neuroimmunology of aging, neurodegeneration, and other aging-related neurological diseases that integrates discovery and translational neuroscience. The program will collaborate with investigators from across Mayo campuses and build upon the many strengths of Mayo Clinic including the Departments of Neuroscience, Neurology, Immunology, Kogod Aging Center and Centers for Individualized Medicine (CIM) and Regenerative Biotherapeutics (CRB). There will be a strong emphasis on application of knowledge and platforms from this program to broad neurodegenerative diseases and aging with a goal to translating these applications to the clinic in a collaborative framework engaging with clinical departments, CRB, and Business Development. The ideal candidate will be poised to take advantage of large-scale, multi-PI RFAs from the NIH, DARPA and other agencies. The candidate will be eligible for Full Faculty privileges and will also be involved in the education of trainees. The position is intended to be located at the Mayo Clinic Arizona site. THE DEPARTMENT OF NEUROSCIENCE is internationally recognized for academic excellence with a specific focus on understanding the etiology and developing diagnostic and treatment methods for complex neurologic diseases, including neurodegenerative dementias, movement, neurovascular, neuroimmune disorders and aging. The Department spans all Mayo Clinic sites and includes 28 primary faculty members, 62 allied health staff, 126 postdoctoral associates, and 36 doctoral students. Scientists within the neuroscience department have strong expertise in neurogenomics, neuropathology, disease modeling, molecular and cell biology, immunity, and experimental therapeutics. The Department faculty play key roles in the Alzheimer’s Disease Research Center and other large-scale NIH-funded consortia. In 2023, the Department of Neuroscience received over $50M in funding, majority of which was from federal grants. Our faculty holds leadership roles on major NIH and foundation programs including but not limited to AMP-AD, CLEAR-AD, Dementia with Lewy Bodies Consortium, Tau Center without walls. Breakthrough innovation doesn’t just occur on its own. It requires focus, hard work, and being connected to the right people, places, and resources to make it all happen. The Mayo Clinic Innovation Exchange is a platform that supports all these needs. Bringing health care entrepreneurs, startups, and industry experts together to bring breakthrough innovations to market. Currently, the Mayo Clinic Innovation Exchange supports over 90 start-ups, all for one shared mission—to benefit patients. Highlights of Mayo Clinic Research Enterprise: + Over 5,000 research personnel, including 317 faculty level research investigators and 909 physicians who are actively involved in research. + 10,505 peer-reviewed papers were published in 2023. + Investments in research each year that result in hundreds of new clinical trials. In 2023, the institution received over $689 million in extramural research awards supplemented with over $446 million of institutional support. + Nearly 10,000 active studies involving human participants in progress. More than 6,050 research grants and contracts. + State-of-the art laboratories and shared resource facilities, including those for microscopy and imaging, cell and molecular biology, animal models, production of iPS cells and clinical grade MSCs, biomedical engineering and mathematics, materials testing, a Medical Genomics Facility, a Mouse Modeling Facility, Molecular and Microscopic Core Facilities, and unique Human Disease Tissue Banks. + Over 420,000 square feet of research laboratory space includes several robotic freezers capable of storing 3.5 million DNA samples. + Mayo Clinic supports innovation and has a wealth of resources available – including an integrated health record and collaboration with top specialists. + Mayo Clinic Brain Bank housed within the Department of Neuroscience and including 11,000 unique brains with neuropathologic characterizations from donors with neurodegenerative diseases and other conditions. About Mayo Clinic Mayo Clinic is top ranked in more specialties than any other care provider according to U.S. News & World Report. With a 73,000-person workforce, Mayo Clinic cares for more than 1.3 million people each year with serious or complex illnesses from all 50 U.S. states and 130 countries. Mayo Clinic is the largest not-for-profit, multidisciplinary academic medical center in the world with over 4,000 physicians and scientists in an integrated multi-campus system spanning the globe. The unified mission at Mayo Clinic is to provide the best patient care, backed by our expertise and supported by innovation in education, research and practice, to bring hope and healing in times of need. We embrace collegial relationships among campuses (Arizona, Florida and Minnesota) allowing for best practices and innovation to help solve the most serious complex medical challenges-one patient at a time. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in a highly competitive compensation package with substantial long-term institutional and departmental support for salary, personnel, equipment, and travel as well as a competitive startup package all designed to ensure immediate and continued success. Additional benefits for faculty at Mayo Clinic include intramural funding opportunities for research and innovation. We provide an outstanding, comprehensive benefits package (https://jobs.mayoclinic.org/benefits) that includes plenty of options for medical, dental and vision care; flexible spending accounts; life insurance; short- and long-term disability coverage; travel allowance; generous time away; and more! We are proud to be among the few U.S. companies to provide a pension benefit at no cost to employees plus you can add the Mayo 403(b) plan which features an employer match. **Qualifications** The successful candidate will have a PhD, MD/PhD, MD (or equivalent degree) with a sustained track record of success in extramural funding (current R01 or R01-equivalent funding as PI), publications, and collaborations with scientists and physicians. Appointment and academic rank will be determined based on the candidate’s qualifications. Successful candidates will be at the level of Associate or full tenured Professor. **Applications should include a full CV/Bibliography, statement of research interests, statement of contributions to equity/inclusion/diversity, and the names/contact information of five references.** As an Affirmative Action and Equal Opportunity Employer, Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available. **Exemption Status** Exempt **Schedule** Full Time **Hours/Pay Period** 80 **International Assignment** No **Recruiter** Natalie Brewster **Equal opportunity** As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.