Chicago, IL, USA
2 days ago
Human Diseases & Immune Discovery (HDID) Core Director

Department

BSD SRF - Human Diseases & Immune Discovery (HDID)


About the Department

The Office of Shared Research Facilities (OSRF) manages BSD Core Facilities by providing financial, administrative, IT, and communication support. OSRF works closely with The University of Chicago Comprehensive Cancer Center and the Research Resources Oversight Committee. The Human Disease & Immune Discovery (HDD) core facility provides expertise, equipment and physical space for researchers to perform cutting-edge, high resolution investigations of human immune system. It leverages innovative technologies from field of flow cytometry for data generation and analysis and can provide cellular component solutions to even higher resolution genomic investigations. HDID provides access to state of the art, 30 parameters cell sorter Symphony S6 from BD Biosciences for physical separation of up to 6 unique cell populations as well as 5 lasers spectral flow cytometer Aurora from Cytek for multiparameter flow cytometry needs. HDID offers comprehensive solutions from sample preparation to data analysis and visualization in one continuous workflow in single, well-equipped location.


Job Summary

The job leads and provides expertise to the development of programs for scientific research facilities. Uses considerable on-the-job experience to ensure compliance of research activities with institutional, state, and federal regulatory policies. Works independently to write articles, reports and manuscripts, and presents research findings at meetings and/or conferences.

The Human Diseases & Immune Discovery Core (HDID) Director oversees all work/study pertaining to flow cytometry, spectral flow cytometry, mass cytometry (CyTOF) and isolation, enrichment and purification of different immune cell subsets from human tissue, preprocessing for a variety of downstream applications, multiparameter flow cytometry data analysis, novel panel development. This role closely collaborates with investigators in experimental design, development, and analysis of flow cytometry-based investigations of the human immune system in steady state; as well as manages all aspects of the Human Disease & Immune Discovery Core (HDID) operations, including staff, graduate students and trainees.

Responsibilities

Directs all aspects of the training, scientific development, and operations of the HDID, reporting directly to the Associate Dean for Research Resources and core faculty advisors.

Provides scientific expertise and leadership in performing and delivering single cell resolution of immune phenotyping analysis, single cell resolution of post-translational protein modification (phosphorylation and acetylation) and immune system related metabolites quantification, and targeted metabolomics data for a variety of research projects in collaboration with Duchossois Family Institute (DFI) investigators.

Oversees the financial, personnel, planning, compliance and other administrative aspects of all research conducted in the HDID core.

Participates in scientific discussions and provides input regarding experimental design, new technological development, and innovation centered on DFI and HDID research themes/studies.

Develops and enforces standard operating procedures (SOPs) for cell sorting, quality control, biosafety, and equipment maintenance.

Works closely with instructs and oversees the HDID research staff, to ensure timely completion of research studies. Train new employees, help expand the core’s capabilities and bring in more users. Mentors and trains research technologists, students and postdocs facilitating their technical growth and development.

Interacts and collaborates with other Platform Directors, OSRF core Directors, faculty and trainees. Ensures alignment with BSD/institutional goals, offering strategic input on experimental design and execution.

Remains an active member of the scientific community by writing scientific articles, publishing manuscripts, and reports, as well as presenting research findings at scientific meetings and conferences. Works on grant applications from start to completion.

Provides expertise to researchers on compliance of research activities with institutional, state, and federal regulatory policies, procedures, directives and mandates.

Provides expertise to researchers and research support staff. Oversees activities related to data collection and analysis.

Leads the establishment of new laboratories and provides assistance with purchasing new laboratory equipment; ensuring efficient operation of laboratory, including overseeing maintenance and repair of laboratory equipment.

Improves financial, personnel, planning, compliance and other administrative aspects of research project. Collaborates with other researchers on long-range plans for research projects. Leads, investigates, modifies and applies new procedures, techniques or applications of technology. Establishes goals and operating procedures, practices, and guidelines.

Performs other related work as needed.     


Minimum Qualifications

Education:

Minimum requirements include a college or university degree in related field.


Work Experience:

Minimum requirements include knowledge and skills developed through 7+ years of work experience in a related job discipline.


Certifications:

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Preferred Qualifications

Education:

Advanced Degree preferably in a field related to the research being conducted.

Experience:

More than 7 years of extensive experience in human and cellular immunology.

Extensive experience in flow cytometry and data analysis.

Demonstrated experience in scientific project design, management, and execution.

Experience in human tissue samples processing.

Prior experience with overseeing staff, technicians, graduate students and trainees.

Preferred Competencies

Strong leadership and mentoring skills.

Ability to analyze and understand complex biomedical research issues.

Commitment to providing a high level of service.

High degree of professionalism while working in a team environment.

Strong problem solving and analytical skills.

Strong interpersonal skills, organizational and writing.

Trustworthy and confident when working with faculty and administrators.

Working Conditions

Laboratory and office environment, combination of walking, standing and sitting, use of computer and specialized laboratory equipment.

Application Documents

Resume (required)

Cover Letter (preferred)


When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.


Job Family

Research


Role Impact

Individual Contributor


Scheduled Weekly Hours

40


Drug Test Required

No


Health Screen Required

Yes


Motor Vehicle Record Inquiry Required

No


Pay Rate Type

Salary


FLSA Status

Exempt


Pay Range

$98,000.00 - $140,000.00

The included pay rate or range represents the University’s good faith estimate of the possible compensation offer for this role at the time of posting.


Benefits Eligible

Yes

The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off. Information about the benefit offerings can be found in the Benefits Guidebook.


Posting Statement
 

The University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, national or ethnic origin, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.

 

Staff Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.

 

We seek a diverse pool of applicants who wish to join an academic community that places the highest value on rigorous inquiry and encourages a diversity of perspectives, experiences, groups of individuals, and ideas to inform and stimulate intellectual challenge, engagement, and exchange.

 

All offers of employment are contingent upon a background check that includes a review of conviction history.  A conviction does not automatically preclude University employment.  Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.

 

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