Department
BSD OBG - Lengyel Lab
About the Department
Our translational research laboratory is in the Center for Integrated Science, a research building on campus that houses 40 independent research groups.
This at-will position is wholly or partially funded by contractual grant funding which is renewed under provisions set by the grantor of the contract. Employment will be contingent upon the continued receipt of these grant funds and satisfactory job performance.
Job Summary
The Department of Obstetrics and Gynecology Lengyel laboratory is looking for a Lab Manager to join its ovarian cancer research team. Specifically, the Lab Manager will be investigating the role of and therapeutic targets of the stroma during ovarian cancer disease progression, and will involve human tissue, in vivo mouse models, three-dimensional organotypic, and primary cell models to perform translational research. The Laboratory Manager will work independently and collaboratively with the principal investigators, fellows, students and other research specialists. The Lab Manager will manage the laboratories Cell and Tissue Banking and Maintenance. The Laboratory Manager will coordinate laboratory jobs, orders, supplies and organization. The Laboratory Manger will train all new employees on specialized equipment including real-time PCR, immunoblotting, and tissue culture. The Lab Manager will meet with company representatives, technical services, and the OSRF core directors to coordinate and successfully complete studies and analysis of these techniques. Under limited direction, the incumbent performs complex lab and/or research-related duties and tasks.
Responsibilities
Assists with planning, development and execution of research in the laboratory.
Manages the organization of the laboratory.
Works collaboratively with the team and collaborators.
Oversees animal protocols, ordering, and organization of colonies.
Manages the cell and tissue banking and organization for team.
Conducts periodic training for current and new members of the laboratory.
Contributes to the writing of academic papers, reports and final summaries.
Collects, records, and analyzes data.
Conducts literature reviews.
Ensures compliance with institutional, state, and federal regulatory policies, procedures, directives, and mandates.
Serves as a lead research specialist.
Presenting research findings at staff meetings, seminars, and scientific conferences.
Takes responsibility for the following non-laboratory duties: transcribing and coding data; developing data collection instruments; presenting research; and recruiting and scheduling research subjects. Acquires higher-level skills and knowledge in the process.
Takes responsibility for the following laboratory duties: recognizing abnormal results and varying conditions or procedures to correct problems; setting up and performing experiments. Analyze the meaning, significance, causes, and effects of the subject.
Applies research principles and relevant subject matter knowledge relevant to administer a research project. With a moderate level of direction, manages lab and/or research-related duties and tasks. Helps develop, design and conduct research projects according to plan.
Supports data collection and analytical needs of research projects. Conducts literature reviews and helps write reports and manuscripts. Ensures project compliance with different policies, procedures, directives, and mandates.
Performs other related work as needed.
Minimum Qualifications
Education:
Minimum requirements include a college or university degree in related field.
Work Experience:
Certifications:
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Preferred Qualifications
Experience:
Two to five years of relevant research experience.
Experience with Molecular Biology techniques (i.e. quantitative real-time PCR, RNA and DNA isolation, transfection, Lentivirus mediated gene silencing, transformation, cloning), Biochemical techniques (i.e. immunoblots), Tissue Culture techniques (i.e. ex vivo cultures, primary cell isolation, transfection, infection, co-culture, three-dimensional modeling), Cell assays (i.e. adhesion, migration, invasion, proliferation, apoptosis, cytotoxicity), Cancer stem cell isolation and culture (human or mouse tumors), Flow cytometry, Microscopy (i.e. immunofluorescent analysis, wound healing assay, immunohistochemical analysis), Mouse in vivo models of cancer metastasis (i.e. intraperitoneal injections and dissections), and Transgenic mouse models (i.e. breeding and genotyping).
Preferred Competencies
Organization.
Problem-solving.
Collaboration and Independence.
Attention to detail.
Communication.
Knowledge in cancer biology and role of microenvironment during cancer progression.
Knowledge of research techniques or methods (cell biology, translation, transcription, primary cultures, microscopy, cell assays, biochemical assays, molecular biology assays).
Knowledge of regulatory policies and procedures.
Strong interest in and commitment to research goals of laboratory.
Required a minimum of two year of experience in research.
Comfort working with a team.
Ability to be flexible in changing research focus.
Experience contributing to research manuscripts, reports, or publications.
Working Conditions
Lab environment.
Ability to stand for extended periods.
Ability to use computer for extended periods.
Application Documents
Resume (required)
Cover Letter (preferred)
When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.
Job Family
Role Impact
Scheduled Weekly Hours
Drug Test Required
Health Screen Required
Motor Vehicle Record Inquiry Required
Pay Rate Type
FLSA Status
Pay Range
The included pay rate or range represents the University’s good faith estimate of the possible compensation offer for this role at the time of posting.
Benefits Eligible
The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off. Information about the benefit offerings can be found in the Benefits Guidebook.
Posting Statement
The University of Chicago is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, or expression, national or ethnic origin, shared ancestry, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.
Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.
All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.
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