Job Family:

Laboratory Technician (Digital)

Travel Required:

None

Clearance Required:

Active Public Trust

What You Will Do:

We are currently searching for a Laboratory Neuroscientist Technician to support the Translational Immunopsychiatry Unit (TIU) of the National Institute of Mental Health (NIMH).  In this role, the technician will assist in developing an integrated clinical, basic, and translational research ecosystem that identifies and characterizes immunologic processes that causally contribute to psychiatric illness, starting with rare autoantibodies in neuropsychiatric disorders. This is a full-time, on-site opportunity in Rockville, MD.  

Collaborate with in-house bioinformaticists, biologists, and biochemists and have opportunities to mentor junior scientists.Contribute to the development of secondary neuroscientific questions stemming from antibody discovery research.Present work at national conferences and publish their findings in peer-reviewed journals.Draft and maintain standard operating procedures for antibody screens and testing.Maintain electronic biospecimen handling and testing logs.Perform primary cell isolation and culture (neurons, astrocytes, oligodendrocytes, and mixed cell culture) and iPSC-derived neuronal cell differentiation and cultures.Conduct human protein array immunostaining (HuProt) and data processing.Sacrifice, perfuse, and cryopreserve mouse brain tissue.Screen for autoantibodies in human biofluids (blood fractions and cerebrospinal fluid) using a variety of methods including, human protein array, immunoprecipitation mass spectrometry (IP-MS) (less commonly) and immunostain rodent and/or non-human primate (NHP) brain tissue with human cerebrospinal fluid (CSF), serum/plasma, and commercial antibodies.Collect, analyze, and interpret data; prepare summaries and reports based on results and findings.Perform advanced equipment maintenance, assist in troubleshooting and calibrating various laboratory equipment and instruments, schedule regular maintenance of equipment logs and maintain performance logs.Prepare presentation slides and figures for outside investigators.Expect to engage with outside investigators for the purpose of interpreting and contextualizing preliminary results; occasionally attend lab meetings of outside investigators.

What You Will Need:

Bachelor’s DegreeAt least ONE (1) year of CLIA-certified lab laboratory experience.Experience in rodent handling and husbandryExpertise in small rodent sacrifice, perfusion, cryopreservation, and paraffin embeddingExpertise in cell line and primary cell cultureExpertise in immunostaining: immunofluorescence, DAB, and colorimetricExperience with handling non-human primates

What Would Be Nice To Have:

NIH experience is beneficialDesired, certification in Clinical Laboratory Improvements Amendments (CLIA)MS Office Suite

What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

Medical, Rx, Dental & Vision Insurance

Personal and Family Sick Time & Company Paid Holidays

Parental Leave

401(k) Retirement Plan

Group Term Life and Travel Assistance

Voluntary Life and AD&D Insurance

Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts

Transit and Parking Commuter Benefits

Short-Term & Long-Term Disability

Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities

Employee Referral Program

Corporate Sponsored Events & Community Outreach

Care.com annual membership

Employee Assistance Program

Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)

Position may be eligible for a discretionary variable incentive bonus

About Guidehouse
Guidehouse is an Equal Employment Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, ancestry, citizenship status, military status, protected veteran status, religion, creed, physical or mental disability, medical condition, marital status, sex, sexual orientation, gender, gender identity or expression, age, genetic information, or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at RecruitingAccommodation@guidehouse.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.