Post Doctoral Associate
Job Description:The University of Florida, Department of Pharmacodynamics is seeking to hire a Post Doctoral Associate in the lab of Dr. Anutosh Chakraborty.
Research focus of the Chakraborty laboratory: Obesity and obesity-induced metabolic dysfunction-associated steatotic liver disease (MASLD) are significant health concerns. A subset of MASLD patients develop liver cirrhosis and hepatocellular carcinoma. A complete knowledge of the mechanisms that cause these diseases is lacking, which hinders the development of safer therapeutic strategies for their treatment. The Chakraborty lab aims to understand mechanisms that regulate the development and progression of these diseases. Using novel, lab-generated mouse models and human patient samples, the lab identifies and validates novel targets in obesity and MASLD and subsequently develops pharmacological tools that ameliorate these diseases by targeting the novel proteins. The lab uses diverse techniques such as proteomics, transcriptomics, lipidomics, cell and molecular biology and pharmacology in cell lines, primary cells and mouse models of obesity and MASLD. Prior work from the lab discovered the inositol hexakisphosphate kinase-1 (IP6K1) and the E3 ubiquitin ligase Ube4A as novel targets in obesity and MASLD (Cell, 2010; JCI, 2016; Mol. Metab., 2016; Biol Rev Camb Philos Soc. 2018; Mol. Metab. 2021; J. Med. Chem., 2022; Biomolecules, 2023; Mol. Metab. 2023).
Job Duties: The Postdoc will be responsible for independently designing and conducting experiments. They will independently obtain, store and organize data and generate figures and write methodologies for manuscripts and grant applications, and present the data at the lab meetings and conferences. The Postdoc will mentor undergraduate and graduate students in the lab and will collaborate in and outside the lab. This position will include working on weekends and holidays when the project requires it.
Chakraborty lab publications: https://pubmed.ncbi.nlm.nih.gov/?term=anutosh+chakraborty&sort=date
The University of Florida College of Pharmacy values the benefit of having a team that consists of diverse talents, skills, strengths, points of view and experiences. The college is committed to cultivating an environment where everyone is respected for their intrinsic value, and developing the next generation of clinicians and scientists who will positively impact the health of others. We’re committed to creating a working environment where everyone can be heard and recognized for their contributions. In recognition of such efforts, the College of Pharmacy is the 3-time recipient of the Insight into Diversity Health Professions Higher Education Excellence in Diversity Award.
Expected Salary:Commensurate with education and experience.
Employment Benefits include: Health Insurance: UF participates in state- and university-sponsored benefits programs for individuals, families and domestic partners, and offers voluntary insurance that includes vision, dental, long-term disability and more. Retirement Options: You may be eligible to participate in the FICA Alternative Plan and other deferred retirement plans. Leave: Full-time post-doctoral associates earn paid leave bi-weekly. To learn more visit: hr.ufl.edu/benefits Minimum Requirements:Candidates must have a Ph.D. in biomedical sciences, encompassing but not restricted to molecular biology, cell biology, biochemistry and physiology; having the necessary skills in cell and molecular biology to study cell metabolism and survival in metabolic diseases.
Preferred Qualifications:Experience in working with primary hepatocyte and adipocyte culture and/or studying ubiquitin and endoplasmic reticulum biology will be a plus. Individuals with exceptional motivation and critical thinking ability, evidenced by high impact publications, are strongly encouraged to apply.
Special Instructions to Applicants:In order to be considered, you must upload your cover letter, resume and list of three professional references.
As a part of our review for research and research support positions, we look for a full CV which includes all professional appointments/engagements, all post-secondary education, and all publications from post-secondary education and all respective dates. Please be sure to not use acronyms in your CV. This CV should include names of entities associated with any projects.
This position is in-person and is not eligible for remote work.
Health Assessment Required: Yes