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Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Title: Post-Doctoral Researcher - Innovative CT Processing

Location: Seattle, WA

At Bristol Myers Squibb we are reimagining the future of cell therapy. With our bold ambition, backed by a best-in-the-industry team and long-term commitment, we are leading the way to unlock the full promise of cell therapy as we strive to put more patients on the path to a cure. If you are ready to challenge yourself, accelerate your career, and give new hope to patients, there’s no better place than here at BMS with our Cell Therapy team.

We are seeking a post-doctoral researcher to design and develop adaptive control schema to advance next generation cell therapy manufacturing. The primary responsibilities of this role are to support the development of mechanistic understanding of process, drug product, and clinical outcome and identify processing strategies to control product attributes during the manufacturing process.

Specifically, this role will support systematic screening of process additives and culture conditions and characterization of CAR T drug product attributes response to perturbation towards the definition of a robust adaptive process control schema that will be implemented in manufacturing workflows. This role provides a unique opportunity to collaborate with a variety of teams within the Cell Therapy Development Organization at BMS and engage in the implementation of innovating processing strategies discovered through this work.

Key Responsibilities:

Support mechanistic model development of cell therapy process and product through high-throughput system perturbation and inhibition experimentationLeverage in-process product characterization, product-outcome correlations and causal experimental results to design and execute adaptive control experimentsUse a wide array of analytical tools to quantify T cell state (flow cytometry, PCR, secreted protein quantification)Perform analysis and interpretation of results with regular presentations to internal working team

Qualifications & Experience:

PhD in immunology, biomedical engineering, cell biology or related disciplinePrevious experience in in vitro culture of primary cells and cell linesExperience in molecular and biochemical laboratory techniques applied to cell characterization including flow cytometry, secreted protein quantification and DNA/RNA extraction, PCRProficient in high dimensional data handling and analysisExcellent written, verbal and presentation skillsHighly-motivated, detail-oriented individual with the ability to multitask and collaborate effectivelyAt least one first-author publication in peer-reviewed scientific journals.No more than 2 years of post-degree experience.Willingness to make 2-3 year commitment

Preferred Skills:

Familiarity executing high-throughput screening techniquesPrevious experience analyzing large data through coding languagesPrevious experience with design, development, execution and analysis of in vivo experiments

The starting compensation for this job is a range from $97,000 - $121,000, plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site. 

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program. 

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If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

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