Posting Description

POSTDOCTORAL ASSOCIATE, Mechanical Engineering (MechE), to work with Professor Domitilla Del Vecchio on a project studying the robust multiplexing of bacterial sensors for environmental monitoring.  The ultimate goal of the project is to engineer bacterial communities that implement multiplexed biosensing, robustly to environmental changes, for deployment in soil or water.  Within this goal, it specifically seeks to develop genetic circuit design tools for the accurate operation of multiple biosensors concurrently in the same bacterial cell, and across multiple cell strains, with performance that is robust to changes in the environment, including temperature and other growth conditions. These biosensors will be in the form of synthetic genetic circuits, including appropriate feedback and feedforward control mechanisms for robustness and accuracy. Genetic circuit architectures that control growth rate will also be required.