School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Post Doctoral Associate 

Duke Department of Neurosurgery 

Brain Tumor Omics Program 

 

 

Position Overview 

We are looking for a dedicated Post-Doctoral Associate to join Dr. Simon Gregory's laboratory in the Brain Tumor Omics Program (BTOP) at the Preston Robert Tisch Brain Tumor Center. This position will involve utilizing cutting-edge single-cell and spatial profiling techniques to explore the mechanisms that drive the development and progression of both high- and low-grade gliomas through independent or collaborative research projects. 

 

Key Responsibilities 

The ideal candidate will have proven experience in generating and analyzing single-cell and spatial profiling data using modern techniques. This work should have contributed to significant pre-prints or published manuscripts, where the candidate played a leading role. Additionally, the successful applicant will have experience in developing and implementing novel assays and technologies, whether for hypothesis-driven research or in collaborative projects aimed at publication or grant applications. 

 

Required Expertise and Technical Skills 

- Strong background in single-cell data generation, spatial profiling, and advanced data analysis. 

- Experience in developing novel assays and technologies, with demonstrated application in research. 

- Proficiency in tissue preparation techniques such as cryotomy and staining. 

- Competence in molecular biology techniques, including DNA/RNA extraction, single-cell data generation, and spatial in situ sequencing. 

- Expertise in analyzing multimodal datasets and implementing new methodologies for glioma characterization. 

 

Preferred Skills 

- Prior experience in research focused on both high- and low-grade gliomas. 

- Strong interest in developing new approaches and implementing advanced technologies to further glioma research. 

 

 

Min Degree Requirements: Ph.D. or equivalent doctorate (e.g. Sc.D., M.D., D.V.M.). Should be used for post-doctoral fellows if the candidate has completed all of the requirements for a degree, but the degree has not been formally conferred; the candidate may present evidence of completion of the degree requirements, together with a statement documenting the date on which the degree is to be conferred. Other Credential/Experiential Requirements: The incumbent must be a true post-doctoral fellow registered with the Post Doc Office and per the following requirements: 

· The term of this appointment is limited (5 years with a possible extension for an additional year) 

· The appointment involves substantially full-time research or scholarship, which may include teaching responsibilities. 

· The appointment is viewed as preparatory for a full time academic or research career. 

· The appointment is not part of a clinical research training program, unless research training under the supervision of a senior mentor is a primary purpose of the appointment. 

· The appointee works under the supervision of a scholar or a department at Duke University. 

· The appointee has the freedom, and is expected to publish the results of his or her research or scholarship during the period of the appointment.

 

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

 

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

 

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.