Apply now to join FAU on its race to excellence. For more information on everything FAU has to offer, please visit www.fau.edu/jobs. Note: Current FAU employees must apply as an internal applicant by logging into their existing Workday employee account. Position Summary: We are seeking a highly motivated postdoctoral candidate with a PhD in cellular and molecular biology, with a strong understanding of biological processes using cell and animal models. The ideal candidate will have a background in neuroscience or closely-related disciplines, with a particular focus on neurodegenerative diseases such as Alzheimer's, Huntington's, or Parkinson's disease. Dr. Subramaniam's lab uses cell and animal models combined with cellular, molecular, signaling and system biology approaches to investigate neurodegenerative disease mechanisms. The SNBI-FAU comprises distinguished faculties, cutting-edge facilities, and is situated on campus, encompassing the Max Planck Institute and the UF-Scripps Research Institute, which provide exceptional opportunities for academic and collaborative studies. Jupiter, Florida, USA, has a population of ~62,000 and is located in Palm Beach County, which is considered one of the nicest places to live in Florida. Jupiter has many restaurants, coffee shops, parks, and wonderful beaches. Jupiter's public schools receive excellent ratings. Key Responsibilities: + Conduct independent research on cellular and molecular mechanisms underlying neurodegenerative diseases. + Utilize cell and animal models to investigate disease pathology and potential therapeutic interventions. + Perform advanced techniques including mouse handling, stereotaxic surgery, and brain imaging analysis. + Analyze and interpret complex data, and present findings in peer-reviewed publications and at scientific conferences. + Collaborate with a multidisciplinary team of researchers and contribute to ongoing projects. + Mentor and supervise graduate students and research assistants. Please review the following examples of publications. 1. Subramaniam S, Sixt KM, Barrow R, Snyder SH. Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity. Science. 2009; PMID: 19498170. 2. Pryor WM, Biagioli M, Shahani N, Swarnkar S, Huang WC, Page DT, MacDonald ME, Subramaniam S. Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease. Science Signaling. 2014. PMID: 25351248. 3. Shahani N, Swarnkar S, Giovinazzo V, Morgenweck J, Bohn LM, Scharager-Tapia C, Pascal B, Martinez-Acedo P, Khare K, Subramaniam S. RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum. Science Signaling. 2016. PMID: 27902448; PMCID: PMC5142824. 4. Sharma M, Jarquin UNR, Rivera O, Kazantzis M, Eshraghi M, Shahani N, Sharma V, Tapia R, Subramaniam S. Rhes, a striatal-enriched protein, promotes mitophagy via Nix. Proc Natl Acad Sci U S A. 2019; PMID: 31676548. 5. Eshraghi M, Ramirez-Jarquin UN, Shahani N, Nuzzo T, De Rosa A, Swarnkar S, Galli N, Rivera O, Tsaprailis G, Scharager-Tapia C, Crynen G, Li Q, Thiolat ML, Bezard E, Usiello A, Subramaniam S. RasGRP1 is a causal factor in the development of l-DOPA-induced dyskinesia in Parkinson's disease. Science Advances. 2020; PMID: 32426479. 6. Eshraghi M, Karunadharma PP, Blin J, Shahani N, Ricci EP, Michel A, Urban NT, Galli N, Sharma M, Ramirez-Jarquin UN, Florescu K, Hernandez J, Subramaniam S. Mutant Huntingtin stalls ribosomes and represses protein synthesis in a cellular model of Huntington disease. Nature Communications. 2021; PMID: 33674575. 7. Ramirez-Jarquin UN, Sharma M, Shahani N, Li Y, Boregowda S, Subramaniam S. Rhes protein transits from neuron to neuron and facilitates mutant huntingtin spreading in the brain. Science Advances. 2022; PMID: 35319973. 8. Ramirez-Jarquin UN, Sharma M, Zhou W, Shahani N, Subramaniam S. Deletion of SUMO1 attenuates behavioral and anatomical deficits by regulating autophagic activities in Huntington disease. Proc Natl Acad Sci U S A. 2022; PMID: 35086928. 9. Rivera O, Sharma M, Dagar S, Shahani N, Ramlrez-Jarquln UN, Crynen G, Karunadharma P, McManus F, Bonneil E, Pierre T, Subramaniam S. Rhes, a striatal enriched protein, regulates post-translational small-ubiquitin-like-modifier (SUMO) modification of nuclear proteins and alters gene expression. Cell Mol Life Sci. 2024; PMID: 38589732. 10. Dagar S, Sharma M, Tsaprailis G, Tapia CS, Crynen G, Joshi PS, Shahani N, Subramaniam S. Ribosome Profiling and Mass Spectrometry Reveal Widespread Mitochondrial Translation Defects in a Striatal Cell Model of Huntington Disease. Mol Cell Proteomics. 2024; PMID: 38447791. Regarding previous work of Dr. Subramaniam's lab, please visit https://www.ncbi.nlm.nih.gov/myncbi/srinivasa.subramaniam.1/bibliography/public/ The College of Science at Florida Atlantic University seeks scholars who are committed to supporting the learning needs of students from diverse backgrounds and to thoughtfully engaging all communities in higher education. Florida Atlantic University embodies a culture of strategic and collaborative community engagement that results in mutual benefit to the institution and the various internal and external communities that it serves. Minimum Qualifications: A postdoc candidate should have a PhD in cellular and molecular understanding of the biological process using cell and animal model. Neuroscience or closely-related disciplines with particular focus on neurodegenerative disease such as Alzheimer, Huntington, or Parkinson is a plus. The candidate should have demonstrated ability of research work through peer-reviewed publications. Postdoc applicants with experience in mouse handling, stereotaxic surgery, and brain imaging analysis are given priority. Salary: Commensurate with Experience College or Department: College of Science Location: John D. MacArthur Campus - Jupiter Work Days and Hours: N/A Application Deadline: 2026-01-01 Special Instructions to Applicant: This position is open until filled and may close without prior notice. This position is subject to funding. All applicants must apply electronically to the currently posted position on the Office of Human Resources' job website (https://fau.edu/jobs) by completing the required employment application for this recruitment and submitting the related documents. Required Documents: FAU’s Career Page permits the attachment of required/requested documentation. PLEASE NOTE: A maximum of five (5) documents may be attached to your application. If more than five (5) documents are required for submission, please combine additional documents into a single attachment to not exceed the maximum permitted. The site permits the attachment of required/requested documentation. When completing the online application, please upload the following: a cover letter, curriculum vitae, and three letters of recommendation. Transcripts: Final candidate will be required to have official, sealed transcripts and original NACES evaluation, if applicable, sent from their educational institution to Human Resources prior to the start of employment. Background Screening: Selected candidates must successfully complete and pass all employment screenings prior to the start of employment. Employment screenings may include a criminal background check (level I and level II), motor vehicle check, credit check, reference checks, alcohol, and drug screening check. Accommodations: Individuals requiring accommodation, please call 561-297-3057. 711 Florida Atlantic University is where your future begins. With over 30,000 students from all 50 states and over 180 countries, 21 intercollegiate teams, 180 plus degree programs, and an administration that thrives on discovery and excellence, Florida Atlantic University is pushing the boundaries of higher education. At FAU, the faculty and staff are trailblazers and innovators with a passion for finding creative solutions while advancing science, art and technology in all disciplines. Student success, excellence and community engagement are some of our highest values as a university. These values are prominent throughout FAU's community and are essential to the employee experience. FAU is committed to the principles of engaged teaching, research and service, and reflects this commitment as a key Platform in its 2015 - 2025 Strategic Plan. Our work environment is a hub of cultures from across the nation and the world, making FAU a place where collaboration flourishes. All persons aspiring to achieve excellence in the practice of these principles are encouraged to apply. To learn more about the vision and mission of FAU, please visit: www.fau.edu In order to be considered for a position, you must apply through this job website. For more information on how to apply for a position, please review the applicable Applicant Tutorial (http://fau.edu/jobs/applicant-resources/) . To contact Recruitment Services, send an e-mail to jobs@fau.edu. Florida Atlantic University is an equal opportunity/affirmative action/equal access institution and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability status, protected veterans status or any other characteristic protected by law. Individuals with disabilities requiring accommodation, please call 561-297-3057. For communication assistance, call 7-1-1. Clery Act Information (https://www.fau.edu/police/clery.php) Florida Statute 1010.35 - Screening Foreign Researchers Pursuant to Florida law, any applicant or student seeking employment in a research or research-related support position who is a citizen of a foreign country and not a permanent resident of the U.S., or who is a citizen or permanent resident but is affiliated with or has had at least 1 year of employment or training in China, Russia, Iran, North Korea, Cuba, Venezuela, or Syria is subject to additional screening. Applicants meeting those criteria will be required to provide the following information before any offer of employment can be made: every institution of higher education attended; all previous employment since the applicant’s 18th birthday; list of all published material, current and pending research funding from any source, including details about the research, your role, funding source, and amount; list and description of any non-university professional activities; any affiliation with an institution or program in a foreign country. Selected applicants will be required to provide additional information per the Statute, including a complete copy of your passport; and, if available, the most recently submitted DS-160 (Online Nonimmigrant Visa Application). Florida Atlantic University is an equal opportunity/affirmative action/equal access institution and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability status, protected veterans status or any other characteristic protected by law. Individuals with disabilities requiring accommodation, please call 561-297-3057. For communication assistance, call 7-1-1.