The Weaver Lab in the Department of Biochemistry and Molecular Genetics at the University of Virginia School of Medicine is seeking a creative and highly motivated Postdoctoral Research Associate to study mechanisms of DNA repair in chromatin.

The Weaver Lab is dedicated to unraveling mechanisms of DNA repair in chromatin and harnessing these mechanistic insights to improve human health. Current research projects in the lab aim to: (1) Determine how DNA damage impacts chromatin structure, stability, and dynamics; (2) Determine how DNA repair enzymes identify and process DNA damage in chromatin; and (3) Determine how chromatin-modifying enzymes regulate chromatin structure to facilitate DNA repair. The lab addresses these research aims using a powerful combination of biochemistry, single-molecule fluorescence microscopy, structural biology, and cellular biology approaches.

The Postdoctoral Research Associate will be involved in full-time research or scholarship at the University. Employment as a Postdoctoral Research Associate is viewed as training and is preparatory for a full-time academic or research career, is supervised by a senior scholar, and allows the appointee to publish the results of their research or scholarship during the training period.

The successful candidate will:

Engage in full-time research or scholarship at the University.

Lead their own research project and significantly contribute to the design, execution, and analysis of experiments related to their research project under the guidance of Dr. Weaver.

Perform rigorous documentation of research records.

Obtain significant training and expertise in advanced laboratory techniques utilized in the Weaver Lab.

Disseminate research findings through peer-reviewed publications and conference presentations.

Prepare and apply for relevant postdoctoral grants and/or fellowships under the guidance of Dr. Weaver.

Assist in the training of undergraduate students, graduate students, and laboratory technicians in advanced laboratory techniques.

MINIMUM REQUIREMENTS:
Education: Doctoral degree
Experience: None
Licensure: None

Preferred Requirements

Candidates should possess a doctoral degree in Biochemistry, Molecular Biology, Structural Biology, or a related Biomedical Sciences field at the time of hiring.

Preferred Skills:

Prior experience in one or more of the following techniques is preferred:

Protein and/or nucleic acid biochemistry (e.g. nucleic acid purification, protein expression and purification, or in vitro reconstitution experiments)

Structural biology techniques (e.g. cryo-EM, X-ray crystallography, or NMR)

Single-molecule fluorescence techniques

PHYSICAL DEMANDS
This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs.

The University will perform background checks on all new hires prior to employment. A completed pre-employment health screen is required for this position prior to employment.

To Apply:

Please apply through the UVA job board, and search for R0068848.

Internal applicants must apply through their UVA Workday profile by searching 'Find Jobs' and search for R0068848.

Complete an application online with the following documents:

Cover letter summarizing past research experience, current research interests, and future career goals.

CV/Resume.

Contact information for at least 3 letters of recommendation.

Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission.  Applications that do not contain all required documents will not receive full consideration.

For questions regarding this position, please contact Dr. Tyler Weaver, Assistant Professor, Department of Biochemistry and Molecular Genetics.

For questions about the application process, please contact Michelle Johnson, Recruiter.

For more information about UVA and the Charlottesville community please see http://www.virginia.edu/life/charlottesville and https://embarkcva.com/.

The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff.  We believe diversity is excellence expressing itself through every person's perspectives and lived experiences.  We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex, pregnancy, sexual orientation, veteran or military status, and family medical or genetic information.