Postdoctoral Research Fellow in Basic and Translational Cancer Research on Therapy Resistance

A Postdoctoral Research Fellow position is available in the laboratory of Dr. Xiangdong Lyu at the Center for Translational Cancer Research, Institute of Molecular Medicine, The University of Texas Health Science Center at Houston (UTHealth-Houston). 

Recruited through a CPRIT Scholar award, Dr. Lyu will join UTHealth-Houston as a tenure-track assistant professor starting from February 1st, 2025. Dr. Lyu conducted research as a DOD Breakthrough Fellowship Awardee at Baylor College of Medicine and MD Anderson Cancer Center. Dr. Lyu received his Ph.D. from Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, and his B.S. degree from Shandong University.

The Lyu lab focuses on understanding how cancer cells sense and respond to stresses from the tumor microenvironment and therapeutic interventions. By investigating the molecular mechanisms of key stress responses and signaling pathways that drive tumorigenesis and resistance to targeted therapy and chemotherapy, the lab aims to develop innovative, mechanism-based strategies to overcome these resistances.

Dr. Lyu has published multiple first/co-first author papers in prestigious journals, such as: Science (PMID: 37676964), PLoS Biology (PMID: 24302888), Cell Research (PMID: 27002220), Development (PMID: 37013244), Journal of Biological Chemistry (PMID: 23532857), Journal of Molecular Cell Biology (PMID: 29924323, and 29432547), Journal of Visualized Experiments (PMID: 32478757).

The Lyu lab is well funded by the CPRIT award ($2,000,000) and generous startup funding from the UTHealth-Houston, enabling cutting-edge basic and translational cancer research.

A recent PhD or equivalent in biology or a related field, or candidates who are soon to complete their PhD.

We are looking for highly self-motivated and collaborative quick learner to join us.

A strong background in molecular biology, biochemistry, cell biology, and/or cancer biology is preferred.

What we do here changes the world. UTHealth Houston is Texas’ resource for healthcare education, innovation, scientific discovery, and excellence in patient care. That’s where you come in.

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100% paid medical premiums for our full-time employees   Generous time off (holidays, preventative leave day, both vacation and sick time – all of which equates to around 37-38 days per year)  The longer you stay, the more vacation you’ll accrue!  Longevity Pay (Monthly payments after two years of service)  Build your future with our awesome retirement/pension plan! 

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Free financial and legal counseling  Free mental health counseling services  Gym membership discounts and access to wellness programs  Other employee discounts including entertainment, car rentals, cell phones, etc.  Resources for child and elder care  Plus many more! 

Position Summary:

A biomedical postdoc position provides an opportunity for early-career researchers to gain valuable experience, develop independent research skills, and contribute to the advancement of scientific knowledge in their field of expertise.

Position Key Accountabilities:

1.    Plans and conducts experiments, analyzes data, and prepares publications describing results.
2.    Assists in training and mentoring of lab personnel, including graduate students and other trainees.
3.    Reads and evaluates literature.
4.    Possess interpersonal skills to effectively collaborate and communicate with individuals at all levels.
5.    Have strong written and oral communication skills.
6.    Performs other duties as assigned.

A recent PhD or equivalent in biology or a related field, or candidates who are soon to complete their PhD.

We are looking for highly self-motivated and collaborative quick learner to join us.

A strong background in molecular biology, biochemistry, cell biology, and/or cancer biology is preferred.

Minimum Education:

Doctoral/Terminal Degree

Physical Requirements:

Exerts up to 20 pounds of force occasionally and/or up to 10 pounds frequently and/or a negligible amount constantly to move objects.

Security Sensitive:

This job class may contain positions that are security sensitive and thereby subject to the provisions of Texas Education Code § 51.215

Residency Requirement:

Employees must permanently reside and work in the State of Texas.