Postdoctoral Research Fellow- CTCR-The Brown Foundation Institute of Molecular Medicine **Location:** Texas Medical Center-Houston, Texas **Category:** Post Doctoral Research Fellow McGovern Medical School at UTHealth Houston Requisition #: 250000AZ **Postdoctoral Research Fellow in Basic and Translational Cancer Research on Therapy Resistance** **A Postdoctoral Research Fellow position is available in the laboratory of Dr. Xiangdong Lyu at the Center for Translational Cancer Research, Institute of Molecular Medicine, The University of Texas Health Science Center at Houston (UTHealth-Houston).** **Recruited through a** **CPRIT Scholar award** **, Dr. Lyu will join UTHealth-Houston as a tenure-track assistant professor starting from February 1** **st** **, 2025. Dr. Lyu conducted research as a** **DOD Breakthrough Fellowship Awardee** **at Baylor College of Medicine and MD Anderson Cancer Center. Dr. Lyu received his Ph.D. from Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, and his B.S. degree from Shandong University.** **The Lyu lab focuses on understanding how cancer cells sense and respond to stresses from the tumor microenvironment and therapeutic interventions. By investigating the molecular mechanisms of key stress responses and signaling pathways that drive tumorigenesis and resistance to targeted therapy and chemotherapy, the lab aims to develop innovative, mechanism-based strategies to overcome these resistances.** **Dr. Lyu has published multiple first/co-first author papers in prestigious journals, such as:** **_Science_** **(PMID: 37676964),** **_PLoS Biology_** **(** **_PMID:_** 24302888 **_),_** **_Cell Research_** **(** **_PMID: 27002220),_** **_Development_** **(** **_PMID:_** 37013244 **_),_** **_Journal of Biological Chemistry_** **(** **_PMID:_** 23532857 **_),_** **_Journal of Molecular Cell Biology_** **(** **_PMID:_** 29924323, and 29432547 **_),_** **_Journal of Visualized Experiments_** **(** **_PMID:_** 32478757 **_)_** **.** **The Lyu lab is well funded by the CPRIT award ($2,000,000) and generous startup funding from the UTHealth-Houston, enabling cutting-edge basic and translational cancer research.** **A recent PhD or equivalent in biology or a related field, or candidates who are soon to complete their PhD.** **We are looking for highly self-motivated and collaborative quick learner to join us.** **A strong background in molecular biology, biochemistry, cell biology, and/or cancer biology is preferred.** **What we do here changes the world.** UTHealth Houston is Texas’ resource for healthcare education, innovation, scientific discovery, and excellence in patient care. That’s where you come in. **Once you join us you won't want to leave.** It’s because we reward our team for the excellent service they provide. Our total rewards package includes the benefits you’d expect from a top healthcare organization (benefits, insurance, etc.), plus: + 100% paid medical premiums for our full-time employees + Generous time off (holidays, preventative leave day, both vacation and sick time – all of which equates to around 37-38 days per year) + The longer you stay, the more vacation you’ll accrue! + Longevity Pay (Monthly payments after two years of service) + Build your future with our awesome retirement/pension plan! **We take care of our employees!** As a world-renowned institution, our employees’ wellbeing is important to us. We offer work/life services such as... + Free financial and legal counseling + Free mental health counseling services + Gym membership discounts and access to wellness programs + Other employee discounts including entertainment, car rentals, cell phones, etc. + Resources for child and elder care + Plus many more! **Position Summary:** A biomedical postdoc position provides an opportunity for early-career researchers to gain valuable experience, develop independent research skills, and contribute to the advancement of scientific knowledge in their field of expertise. **Position Key Accountabilities:** 1. Plans and conducts experiments, analyzes data, and prepares publications describing results. 2. Assists in training and mentoring of lab personnel, including graduate students and other trainees. 3. Reads and evaluates literature. 4. Possess interpersonal skills to effectively collaborate and communicate with individuals at all levels. 5. Have strong written and oral communication skills. 6. Performs other duties as assigned. **A recent PhD or equivalent in biology or a related field, or candidates who are soon to complete their PhD.** **We are looking for highly self-motivated and collaborative quick learner to join us.** **A strong background in molecular biology, biochemistry, cell biology, and/or cancer biology is preferred.** **Minimum Education:** Doctoral/Terminal Degree **Physical Requirements:** Exerts up to 20 pounds of force occasionally and/or up to 10 pounds frequently and/or a negligible amount constantly to move objects. **Security Sensitive:** This job class may contain positions that are security sensitive and thereby subject to the provisions of Texas Education Code § 51.215 **Residency Requirement:** Employees must permanently reside and work in the State of Texas. If you are looking for a great healthcare career in Houston, visithttp://go.uth.edu/careers! **University of Texas Health Science Center at Houston (UTHealth)** Established in 1972 by The University of Texas System Board of Regents, The University of Texas Health Science Center at Houston (UTHealth) is Houston’s Health University and Texas’ resource for health care education, innovation, scientific discovery and excellence in patient care. The most comprehensive academic health center in the UT System and the U.S. Gulf Coast region, UTHealth Houston is home to schools of biomedical informatics, biomedical sciences, dentistry, nursing and public health and the John P. and Kathrine G. McGovern Medical School. UTHealth Houston includes The University of Texas Harris County Psychiatric Center, as well as the growing clinical practices UT Physicians, UT Dentists and UT Health Services. The university’s primary teaching hospitals are Memorial Hermann-Texas Medical Center, Children’s Memorial Hermann Hospital and Harris Health Lyndon B. Johnson Hospital. **UTHealth Benefits** UTHealth Houston offers a comprehensive and competitive benefits package. For more information on our benefits programs please refer to the UTHealth Houston Office of Benefits Website. https://www.uth.edu/benefits/ **Equal Employment Opportunity Statement** UTHealth Houston is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth Houston policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law. UTHealthHoustonhas adopted a policy consistent with CMS regulations to protect our patients and university community from exposure to COVID-19. This policy affects all employees, residents, fellows, students, contractors, new hires, visiting scholars program participants, adjunct faculty, and volunteers who work, train, or collaborate at the John S. Dunn Behavioral Science Center. In addition, all UTHealthHouston​​​​​​​employees who are assigned to work at a location that is subject to the affiliated partner’s hospital, clinical offices, or agency are required to abide by UTHealth’sHoustonrules and regulations, as well as the affiliate’s rules and regulations, including COVID-19 vaccination and safety requirements. Work location is based on the needs of the department and may be adjusted.