**Job Description** The Karlstaedt Lab is looking for a Postdoctoral Fellow to join an ambitious collaborative project to decipher metabolic interactions between cancer cells and the heart. Funded in part by an active NIH/NHLBI grant, this role will involve a close collaboration in a multidisciplinary team together with collaborators within the Smidt Heart Institute and the Cedars Cancer Center. Our research group has an established track record in the study of metabolic pathways using in vivo and ex vivo multi-omics approaches, including computational simulations of cardiac metabolism. We combine ex vivo organ perfusion techniques with stable isotope tracers to measure metabolic flux alterations. The successful candidate will have significant autonomy to develop innovative strategies for projects bridging cardiovascular research and oncology. A unique opportunity within the research group is to establish in vivo mouse models to study metabolic changes in the heart during cancer. Currently, a particular focus is on leukemia and solid tumors (e.g., colorectal cancer). The position will also be connected to a vibrant local scientific community for translational research in Los Angeles. We seek to build on previous expertise and methods devised by our team. Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientist, our Research Fellow will perform routine and complex laboratory procedures throughout training period and may develop, adapt, and implement new research techniques and protocols. Will analyze and interpret data and may assist in preparation of grant proposals. You will participate in publications and presentations as author or co-author. This position is not responsible for generating grant funds. ESSENTIAL JOB DUTIES AND RESPONSIBILITIES: + May assist in preparation of grant proposals, but is not responsible for generating grant funds. + May participate in publications and presentations as author or co-author. + Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. + May develop, adapt, and implement new research techniques and protocols. + Analyzes, interprets, summarizes and compiles data. + Performs routine and complex laboratory procedures throughout training period. + Operates and maintains equipment and instruments. Application Process: + Applications should include (in a single PDF) + Please include a cover letter along with your CV + Please include a publication list + Projects you are interested in and your career goals **Qualifications** Educational Requirements: + Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization is required Experience: + Works independently on research projects designed by a mentor (typically the PI) within area of specialization. + Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. + Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment. + Knowledge of safety standards and maintenance of specialized equipment. + Knowledge of mass spectrometry, tracer studies and transgenic mouse models. + Expertise in biological data science and data-driven discovery, scientific programming and omics data analysis, genetics will also be beneficial, as is communicating results in scientific conferences and papers. **About Us** Cedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. **About the Team** Cedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. **Req ID** : HRC0891230 **Working Title** : Postdoctoral Scientist - Smidt Heart Institute - Karlstaedt Lab **Department** : Heart Institute **Business Entity** : Cedars-Sinai Medical Center **Job Category** : Academic / Research **Job Specialty** : Postdoctoral Scholar **Overtime Status** : EXEMPT **Primary Shift** : Day **Shift Duration** : 8 hour **Base Pay** : $30.00 - $45.00 Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.