Boston, MA, US
5 days ago
Principal Scientist - Breast Oncology Translational Research
Welcome page Returning Candidate? Log back in! Principal Scientist - Breast Oncology Translational Research Location US-MA-Boston Job Posted Date 5 hours ago(11/14/2024 9:14 AM) Job ID 2025-42139 Category Research-Laboratory Type full time Grade 49 Location : Address 450 Brookline Ave Location : City Boston Overview

The Department of Breast Oncology at Dana-Farber Cancer Institute seeks a Principal Scientist to join our efforts in identifying better treatments for our patients with breast cancer and leading our translational research team. We are applying innovative methods in multiple clinically oriented studies to help advance efforts for precision cancer medicine. The Principal Scientist, in collaboration with faculty leaders in our division and Translational Hub, principal investigators, computational biologists and senior director of cohort and translational studies, will be involved in leading cross-disciplinary efforts to perform translational research to develop new therapies to improve outcomes. The aim of these efforts will be to characterize mutations by describing evolutionary dynamics and identifying mechanisms of resistance and predictors of therapeutic benefit. These new data could help identify novel approaches for personalized care in oncology.  In addition, these studies will support research that will leverage new methods in clinical decision-making, biomarkers for rational drug development, and new insights into tumor biology through innovative analyses.

 

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

 

Responsibilities

The ideal candidate will be passionate about developing a career of scientific discovery, contributing as a highly-motivated leader and team player, and helping lead translational research to help improve patient outcomes and treatment options in collaboration with the faculty leaders and principal investigators. The individual will also have opportunities to develop mentorship skills through supervision of junior members of the team.

Lead and participate in the development of clinical trials and scientific projects by contributing to the design and review of correlative science and translational work outlined in the studies, in collaboration with faculty, Translational Hub, research investigators, as well as internal and external collaborators.Supervise the Associate Director of Translational Research and the Translational Research Team of project/program managers and research data specialists in the execution of clinical trials and translational studies to ensure the proper processes related to preparation, collation, and transfer of biospecimens for specific studies and the coordination and management of the overall translational infrastructure to support all studies.Oversee the execution of the design of the studies in the preparation, collation and transfer of biospecimens for the correlative and translational component of the studies.Collaborate with a group of multidisciplinary scientists in the laboratory and our breast oncology computational group, along with larger research groups such as the Broad Institute and external collaborators to achieve the aims of our translational work.Work closely with Translational Hub manager and Senior Director of Cohort and Translational Research to ensure coordination with the Breast Oncology’s research activities.Provide training and mentoring of scientific methods related to biospecimen requirements and analysis for the junior members of the team.Under mentorship of principal investigator, develop research with innovative assays and technologies focused on breast cancer in role as staff scientist that can be applied to the Division’s priority translational work.

 

Qualifications

 

A Ph.D. in molecular biology, cellular biology, cancer biology or related discipline.Relevant scientific and lab management experience.Enthusiastic team player, innovative and analytical thinker and self-motivated individual.Excellent analytical, organizational and management skills to prioritize multiple scientific projects and to supervise a group of interdisciplinary team members.Outstanding written and verbal communication skills.Strong interpersonal skills to effectively collaborate with all levels of lab members, staff and external collaborators.

 

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.  As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.  Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

 

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

 

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