At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$63,000 - $162,800

The Bioproduct Research and Development organization strives to deliver creative medicines to patients through the development and commercialization of insulins, monoclonal antibodies, novel therapeutic proteins, peptides, oligonucleotide therapies and gene therapy systems. This organization is a multidisciplinary group that works collaboratively with our discovery and manufacturing colleagues. Located in Indianapolis, scientists have full access to our scientific excellence and engineering capabilities.

Do you enjoy downstream drug substance processes including purification and filtration of monoclonal antibodies, recombinant proteins, viral vectors, bioconjugates, and peptides?  Do you have experience using automation and high-throughput screening to guide process development? Do you have experience automating data collection, analysis, and display to aid interpretation? Are you skilled in the analytical techniques used to characterize bioproducts? If so, then a role as a Purification Development Scientist with expertise in high-through process development (HTPD) is waiting for you!

As a scientist in the Purification Development group, you will work to design efficient and effective downstream drug substance processes for new biologic candidates as they make their way from discovery to the clinic. Work responsibilities will vary, and you should be flexible and adaptable in accepting new projects and challenges, guided by your supervision. The ability to troubleshoot issues as they occur, and to identify trends and opportunities to reduce process variability, are also key.  This role is expected to include an initial period dedicated to HTPD and supporting activities, and over time will transition to flexibly divided time between HTPD and general process development.

The ability to exhibit a high level of attention to detail and a quality-minded approach to record keeping is crucial.  Maintaining accurate records and interpreting data to provide detailed information and analysis on the execution of experiments will be a daily activity.  Writing technical reports, tech transfer documents and giving presentations to summarize development activities are important deliverables.

This role requires effective interaction and communication of technical information with, but not limited to; Safety, Environmental and Quality Team members, Purification Development colleagues, CMC Team members, Discovery team members, Analytical Services, Tech Service/Manufacturing Science representatives, Operations, Engineering, Regulatory and Maintenance personnel.

Especially important, in this role, is that you adhere to all safety and environmental guidelines and promote a proactive safety culture and environmental compliance in all areas.

Basic Qualifications:BS/MS in Chemistry, Biochemistry, Chemical Engineering, or related degree

OR

At least 3 years relevant experience in protein purification/process developmentAdditional Skills/Preferences:Experience or familiarity with high-throughput process development using resin filter plates and/or miniature columns (such as RoboColumns)Experience or familiarity with Tecan liquid handling robotic systems or similar systems (such as Hamilton)Experience with programming robotic systems and/or general programming, including VBAExperience with collecting, organizing, and interpreting data (such as Kp) from high-throughput chromatography process development, especially leveraging automation in the data workflowOperation of column chromatography on ÄKTA systemsOperation of analytical methods on HPLC systemsEffective oral and written communication skills.Strong laboratory skillsAbility to interact and form dynamic relationships with a wide range of groupsExperience with process control and documentation systems (Unicorn, Empower, electronic laboratory notebooks)General interpersonal and communication skills; mentoring, feedback, training, and encouraging an environment for learning and open/honest communication.Basic analytical skills and understandingAdditional Information:Location: Indianapolis, IN. LTC-N

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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