The OHSU Knight Cancer Institute is a pioneer in personalized cancer treatment and research, led by Dr. Brian Druker, whose development of Gleevec transformed Chronic Myeloid Leukemia from a fatal disease to a manageable one and proved that targeted therapies can work. The institute focuses on precision oncology, the early detection, prevention, and treatment of cancer, and creating a welcoming and supportive environment for its caregivers, researchers, and support personnel. Knight affiliates subscribe to three guiding principles: we are bold, we are supportive, and we work as a connected team in our fight to end cancer as we know it. We’d love for you to join us!
A research assistant 2 position is available for a motivated candidate to join the Saultz laboratory in the Leukemia Center within the Knight Cancer Institute at Oregon Health & Science University (OHSU). The OHSU Knight Cancer Institute is a world leader in treating leukemia. Our director, Dr. Brian Druker, is an internationally recognized pioneer in precision cancer medicine. Dr. Druker played a central role in developing Gleevec, a daily pill for chronic myelogenous leukemia (CML) that has saved tens of thousands of lives. The Saultz lab focuses on the immune system, particularly NK cells, and how to augment NK cellular therapy in AML.
Function/Duties of PositionThis position will assist in research that shows how NK cell recognition of the tumor may change throughout treatment and how could we use the leukemia specific vulnerabilities, including the maturation state of the stem cell and genetic alterations to develop improved immunotherapy strategies for AML patients.
1. Every Knight Cancer employee is expected to embody our guiding principles:
We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differentlyWe SUPPORT each other—Respect leads to trust, which leads to excellenceWe work as a CONNECTED team — We must leverage our collective brain power to conquer cancer because no one individual can do it alone2. Maintain long-term tissue cultures for experimental purposes.
3. Plan and perform experiments related to the research goals of the project, including Molecular and cellular biology assays, flow cytometry, mammalian cell culture, biochemistry assays, utilization of in-vivo models and associated techniques, cell isolation and DNA/RNA purification from bacterial cultures, mammalian cell cultures, in-vivo models and patient samples.
4. Perform functional drug screening and CRISPR/Cas9 library screens on cell lines.
5. Collect, record, organize and analyze data.
6. Read literature, data and figure preparation, attend and present at lab meetings.
7. Isolate and Expand human NK cells
Required QualificationsEducation & Experience:
Bachelor's in relevant fieldOR Associate's AND 3 years of relevant experienceOR 4 years of relevant experienceOR Equivalent combination of training and experienceJob Related Knowledge, Skills and Abilities (Competencies):
Ability to prioritize multiple tasks at one timeAbility to learn new experimental and analytical techniquesMust have a high sense of responsibility, analytical and organizational skillsAbility to work independently and as part of a team while being collaborative in resolving problemsMust be proficient with computers running Windows and PC applications e.g. MS Excel, Access, Word and PowerPoint)Task-oriented and are flexible with different working schedules Preferred QualificationsEducation & Experience:
Bachelor’s degree in science or technologyPrior laboratory experienceJob Related Knowledge, Skills and Abilities (Competencies):
R or other computational Data Analytics method Additional DetailsApply online. Please be sure to upload a Cover Letter and Resume/CV.
We offer a variety of benefits on top of joining a thriving organization:
Medical, dental and vision coverage at no or low cost to employees Covered 100% for full-time employees and 88% for dependents Several retirement plans to choose from with contributions from OHSU 25 days a year of paid time off 8 days of sick time off Commuter subsidies Tuition reimbursement Access to group life insurance, disability insurance and other supplemental benefits Annual Merit Increase Growth/Development Opportunities
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All are welcome Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.