Description Independently, develop, optimize, and proactively troubleshoot cellular screening assays. ● Responsible for generating, processing, interpreting, and presenting data in cross functional team meetings ● Proactively employ cell and molecular biology techniques, including gene targeting approaches and small molecule inhibition, to dissect mechanism of action. ● Independently design, execute and document experiments to evaluate target dependency, off target liabilities, phenotypic responses and identifying resistance mechanism Experience in developing and optimizing cell-based assays in multiple platforms (for example CTG, HTRF, AlphaLISA , FC, Jess-WB, NanoBret, Nanostring). ● Experience with different molecular and cellular biology techniques (such as Western Blot). ● Experience with genome editing (CRISPR or si/shRNA) for engineering cell line models is a plus. ● Familiar with tumor models and establishing PK/PD/efficacy relationships and delivering PD readouts by western blots for in vivo tumor models Skills Biology, cell based assay, molecular biology, cell-based assays, cell culture, genomic editing, crispr, tumor models, HTRF, CTG, AlphaLIS, sirna Top Skills Details Biology,cell based assay,molecular biology,cell-based assays,cell culture,genomic editing,crispr,tumor models Additional Skills & Qualifications MS/BS in oncology, cellular biology, molecular biology, or related discipline with 1+ years of industry or relevant research experience is required. Experience with standard software analytical tools, xlsx, Prism, or other synergy software Experience Level Intermediate Level Pay and Benefits The pay range for this position is $40.00 - $60.00 Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave) Workplace Type This is a fully onsite position in Cambridge,MA. Application Deadline This position will be accepting applications until Dec 31, 2024. About Actalent Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. Diversity, Equity & Inclusion At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I are embedded into our culture through: + Hiring diverse talent + Maintaining an inclusive environment through persistent self-reflection + Building a culture of care, engagement, and recognition with clear outcomes + Ensuring growth opportunities for our people The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law. If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com (%20actalentaccommodation@actalentservices.com) for other accommodation options.