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Job Summary

The laboratory of Dr. Karl Desch at the University of Michigan is seeking a postdoctoral fellow to join our lab and concentrate on the molecular genetics of bleeding and thrombotic disorders in humans.

The Desch laboratory investigates the genetic determinants of complex phenotypes that surround the maintenance of hemostasis and the avoidance of hemorrhage or excessive thrombosis. We have developed expertise in computational genetics (genome-wide association studies, rare variant association studies, mendelian randomization) and bench based genetic screens (phage display, deep mutational scanning, lentivirus delivered CRISPR targeting and proximity labeling proteomics). The lab is made up of undergraduates, PhD students and post-doctoral fellows and uses basic cell and molecular biology techniques to answer questions regarding the role of human genetic variation in thrombosis and hemostasis. Research work is primarily funded by the NIH-NHLBI and participants in lab will be supported to write grants of their own as well. Dr. Desch is an internationally recognized scientist in the field of hemostasis and thrombosis. He serves on ad hoc NIH F30/F31/F32 and R01 study sections as well as American Society of Hematology Scholar study sections and until 2023 on the scientific subcommittee on Epigenetics and Genomics. Dr. Desch currently serves as an associate editor for the Journal of Thrombosis and Haemostasis focusing on manuscripts using genomic tools, von Willebrand factor biology, thrombotic microangiopathies and/or pediatric populations. He also serves on the variant curation expert panel for von Willebrand disease as a part of ClinGen. I am an active clinician in Neonatal-Perinatal medicine at the University of Michigan, Ann Arbor.

Required Qualifications*

We are looking for a highly motivated and ambitious scientist with a doctoral degree in a biological science discipline. The successful candidate is expected to conduct research independently under the supervision of the PI. Prior experience in basic molecular and cellular biology is required. Applicants with expertise in areas including but not limited to, cell imaging, flow cytometry, protein-protein interactions are preferred.

Interested applicants should email Dr. Karl Desch directly at [email protected] with a cover letter describing research experiences and interests, curriculum vitae, and contact information for three letters of reference.

Modes of Work

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.