For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about. **Job Summary** We are looking for a **Research Specialist IV - Lab Manager** to join our **Insourcing Solutions** team, located **in Bethesda, MD.** **Why work at Charles River?** We adhere to strong values, share the same mission, that together, we create healthier lives. Our culture is one of endless opportunity, purpose and creating change. We are committed to empowering our employees with the tools and programs they need to develop rewarding careers. We offer competitive benefits and excellent training programs for all our employees. **What impact you will have!** In the **Research Specialist IV - Lab Manager** role, you will provide research and technical support services, working in partnership with research staff members in biomedical research. The essential duties of the Research Specialist IV - Lab Manager are: + Plan, execute, and arrange laboratory experiments + Develop new techniques and procedures + Performs laboratory techniques relating to scientific research, including molecular biology and cell/tissue culture maintenance + Operates laboratory machines and instruments; and prepares specimens and equipment for use. + Performs sample management and storage + Maintain a detailed electronic lab notebook to ensure replicability of laboratory experiments + Trains/onboards new lab members in performing routine laboratory procedures and protocols + ​​​​Perform molecular biology tasks (e.g. PCR, cloning, restriction digests, gel electrophoresis, sequencing and verification of constructs, making mRNA, DNA isolation, RNA isolation, etc.) + Perform tasks related to human samples (cataloging, DNA isolation, RNA isolation, generate LCLs, isolates pBMCs, CD31+ bead selection, generate fibroblast lines, etc.) + Perform zebrafish related tasks (Blast comparison to human genome, genotype zebrafish, zebrafish microinjection, zebrafish microscopy, drug screening, western blotting, maintenance of zebrafish lines- including coordinating import and export etc.) + Cell related tasks: (cell culture, transfection, transduction, making organoids, western blotting, immunostaining, microscopy, etc.) + Data analysis of experiments including using appropriate statistical analysis + Create figures including but not limited to graphs, images + Participate in lab meetings, present findings at both internal lab meetings and local, national, international conferences as appropriate + Write and publish manuscripts + Assist other members in lab with 2 person projects as needed + Lab organization/lab management **Who are we looking for?** The following are minimum qualifications related to the **Research Specialist IV - Lab Manager** position: + Ph.D. in Microbiology and Molecular Biology + Minimum of four (4) years related experience + Strong communication skills, both oral and written + Excellent organizational and time management skills **The pay for this position is $95,000-$104,000 USD per year.** Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location. **About Insourcing Solutions** Charles River Insourcing Solutions℠ can streamline research by delivering operational and cost efficiencies through the strategic insourcing of GMP, GLP and non-GLP research services from discovery through safety assessment. Insourcing Solutions℠ provides you with the ability to maintain control of your facility and expertise while leveraging available space. **About Charles River** Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021. **Equal Employment Opportunity** Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, or national origin, veteran or disability status. If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications. For more information, please visit www.criver.com. 225206