Charlestown, MA, United States of America
19 hours ago
Research Technician
Site: The General Hospital Corporation


 

At Mass General Brigham, we know it takes a surprising range of talented professionals to advance our mission—from doctors, nurses, business people and tech experts, to dedicated researchers and systems analysts. As a not-for-profit organization, Mass General Brigham is committed to supporting patient care, research, teaching, and service to the community.  We place great value on being a diverse, equitable and inclusive organization as we aim to reflect the diversity of the patients we serve.

At Mass General Brigham, we believe a diverse set of backgrounds and lived experiences makes us stronger by challenging our assumptions with new perspectives that can drive revolutionary discoveries in medical innovations in research and patient care. Therefore, we invite and welcome applicants from traditionally underrepresented groups in healthcare — people of color, people with disabilities, LGBTQ community, and/or gender expansive, first and second-generation immigrants, veterans, and people from different socioeconomic backgrounds – to apply.


 


 

Job Summary

Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data.
Does this position require Patient Care?
No
Essential Functions
Perform laboratory experiments following established protocols and procedures.
Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
Record experimental data accurately and maintain organized records of procedures, protocols, and results.
Compile and analyze data using appropriate statistical and analytical methods.
Assist in data interpretation and presentation, contributing to research findings and reports.


 

Qualifications

Education
Bachelor's Degree in Biology required.
Experience
Prior laboratory experience, either through academic coursework, internships, or employment. 1-2 years preferred

**HANDS-ON LAB EXPERIENCE**

**FULL TIME ROLE**

**GRADUATED MAY 2025 OR SOONER**

Knowledge, Skills and Abilities
- Strong theoretical and practical knowledge of laboratory techniques and procedures.
- Familiarity with common laboratory equipment and instruments used in research experiments.
- Proficiency in data collection, analysis, and scientific software tools.
- Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
- Strong problem-solving skills and the ability to troubleshoot technical issues.
- Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.


 

Additional Job Details (if applicable)

The Rivera laboratory is part of the MGH Pathology Department and MGH Cancer Center and we are also affiliated with the Broad Institute. Our work is focused on using genomic technologies to identify and characterize abnormal gene regulation pathways that drive cancer cells and new approaches to modulate them. Our studies involve the integration of biochemistry, cell biology and genome-wide profiling of chromatin and transcriptional states (such as ChIP-seq, ATAC-seq, RNA-seq, Hi-ChIP and HiC). Using these approaches, our laboratory has uncovered gene regulation networks and new mechanisms of chromatin regulation in a variety of tumor types, including medulloblastoma (Boulay et al, Cancer Discovery 2017) and Ewing sarcoma (Riggi et al, Cancer Cell 2014; Boulay et al, Cell 2017). We have also developed new technologies to study chromatin states associated with repetitive elements and disordered proteins (Tak et al, Cell Genomics 2022; Xing et al, Nature Biotechnology 2023. Research technicians will join a collaborative group of scientists working on cutting edge research.

As members of the team, research technicians are expected to work closely with postdoctoral fellows and contribute experimentally to one or several research projects in the laboratory. Contributions will include: setting up and performing experiments, assisting with hypothesis generation, experimental design and data interpretation.  Common assays include western blotting, qPCR, cloning, RNA/DNA isolation, genomic assays (e.g. ChIP-seq, RNA-seq), lentivirus production, general mammalian cell culture, compound screening.


 

Remote Type

Onsite


 

Work Location

149 Thirteenth Street Building 149


 

Scheduled Weekly Hours

40


 

Employee Type

Regular


 

Work Shift

Day (United States of America)


 

EEO Statement:

The General Hospital Corporation is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.


 

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

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