Job Title: RNA Machine Learning Fall 2025 Co-op – Vaccine

Location: Waltham, MA

About the Job

At Sanofi, we chase the miracles of science, and we know mRNA has a role to play in the future of health. And while the pandemic has shaken up our industry, creating new opportunities and risks, we believe the acceleration of innovation with mRNA technology means vaccines and treatments for more people faster than before.

That’s why we’re looking for bold, optimistic world-changers to join our mRNA Center of Excellence. We’re investing €400m a year into the new Center, hiring a team of 450 dedicated employees, and focusing on implementing an integrated end-to-end mRNA vaccine capabilities and research with R&D, digital and CMC teams.

Bring your ambition and optimism and join us on our journey to discover and deliver transformative medicine to patients through the advancement of our cutting-edge mRNA technology!

As an RNA Machine Learning Co-op, you will participate in a 6-month project in the areas of cheminformatics, bioinformatics, computational biology, and machine learning to the task of developing and implementing first-in-class and best-in-class computational solutions and models for screening, optimizing and evaluating RNA molecules for mRNA-based vaccines and therapeutics as part of the Data and Computational Science team in the mRNA CoE. This team brings end-to-end data integration and advanced analytics (pre-clinical, biomarkers, process development, CMC, clinical) in the mRNA CoE. Deploying and exploiting digital solutions (AI/machine learning, data, analytics) to integrate the full data value chain, extracting actionable information for a move to a full data driven strategy and decision-making process, to increase probability of success and to accelerate mRNA vaccines and therapeutics development and launch.

We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.

Main Responsibilities:

Collaborate with group experts in the development and execution of the scientific strategy and technical solutions to develop best-in-class mRNA vaccines and therapeutics

Execute development of a project to deliver data and computational solutions for the integration of chemical, structural, and biological data to support data analytics and visualization

Design, develop, and validate robust analytical and machine learning approaches to support in silico characterization, screening, optimization, and analysis of mRNA molecules

Collaborate internally to develop scientific hypotheses and drive new scientific insights based on computational frameworks

Develop, deploy, and assess the results of at-scale models at varying levels of model granularity encompassing heterogeneous preclinical and clinical data

Employ machine learning methods such as deep learning, neural networks, reinforcement learning, graphical, and generative models to deconvolve high dimensional experimental and in silico modeling results

Maintain a well-documented, reusable codebase, and traceable model history

Maintain awareness of latest developments in relevant fields, evaluate and apply as warranted

Demonstrate good software engineering practices

Proactively identify, assess, and internalize emerging technologies and methods

About you:

**At this time, Sanofi will not sponsor a new applicant for employment authorization or offer any immigration related support for this position (i.e. H1B, F-1 OPT, F-1 STEM OPT, F-1 CPT, J-1, TN, or another type of work authorization). ** 

Basic Qualifications:

Currently pursuing a PhD or master's degree in Cheminformatics, Bioinformatics, Computational Chemistry, Computational Biology, Computer science, or related quantitative disciplines at an accredited college or university with the expectation that you will complete your current degree by the Spring of 2027

Must be enrolled in school the semester following your internship/co-op with Sanofi 

Must be able to relocate to the office location and work 40hrs/week, Monday-Friday, for the full duration of the co-op/internship

Must have permanent US work authorization 

Experience in computational and statistical analysis, quantitative modeling, and machine learning algorithms

Preferred Qualifications:

Fluency in scientific computing (e.g., python, R)

Practical experience proposing, prototyping, and deploying novel algorithms; developing and validating new models

Demonstrated record of transforming algorithms/theory into practical applications delivering robust models that are high performance, interpretable and actionable

Experience with software development good practices (code versioning, testing, etc.)

A creative problem solver, skilled in divergent thinking and turning complex data into actionable insights and knowledge

Good communication, scientific writing, and presentation skills; ability to simplify complex problems and communicate complex solutions in a simple and effective manner

Understanding of vaccine development processes is a plus, as well as familiarity with RNA processes and RNA-centric techniques/methods

Fluent in English

Why Choose Us?

Bring the miracles of science to life alongside a supportive, future-focused team.

Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

Why Choose Us?

Bring the miracles of science to life alongside a supportive, future-focused team.

Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.