The TPD proteomics core at Dana-Farber Cancer Institute is a research core focused on the development and application of state of the art mass spectrometry-based discovery pipelines for targeted protein degradation and molecular glues. The TPD proteomics core is closely affiliated with the Fischer lab and the chemical biology program and serves Dana-Farber researchers and discovery partnerships.
The TPD proteomics core seeks a highly motivated individual to join the team as a RESEARCH SCIENTIST I, who will work with the team to develop and molecular glue discovery pipelines. This role involves developing and testing large scale discovery pipelines using mass spectrometry or other omics approaches, leading projects, and interacting with partners and other stakeholders to successfully perform discovery screens.
This is an excellent opportunity to work in a vibrant environment and to apply state of art computational methods to support cutting edge biological research both within the lab and the Dana-Farber Cancer Institute as well as through collaboration with external laboratories and industry. https://fischerlab.dana-farber.org/
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Responsibilities
Performs RNAseq and proteomics sample preparation and data analysis
Establish a bioinformatics pipeline to assess protein and transcript expression patterns across sample typesEstablishes an imaging and/or flow cytometry-based workflow for quantitative validation of potential target proteinsResponsible for cell culture and performing drug treatmentsAnalyze experimental data and interpret results to write reports, presentations, grant and publication preparationMaintains detailed notebook of all work-related activitiesMaintains highly organized sample and data tracking and reporting workflowsCollaborates with other lab members for the development, modification and improvementof standard operating procedures
QualificationsRecent Ph.D. or equivalent degree in biology, biochemistry, or mass spectrometry
Strong understanding of statistical and computational methods
Experience in working with large data projects
Ability to collect and analyze experimental data, prepare research publications and communicate results
Ability to work in a collaborative and team environment
Excellent oral and written capabilities
Experience with R, MATLAB, or python and general computational abilities
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEOC Poster
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