Worcester, MA, 01613, USA
3 days ago
Scientist II
Description Contractor Scientist II - Biologics Developability Screening and Automation The Biologics CMC Developability team is an integral part of the Biologics CMC Drug Product Development organization. The Biologics CMC Developability team conducts high-throughput screening of physicochemical properties of discovery-stage biologic drug candidates to identify liabilities helping in the selection of lead candidates for pipeline advancement. Key Responsibilities: - Conduct laboratory-based high-throughput screening and analytical biophysical and biochemical characterization of biologic drug candidates. Perform experiments to screen physicochemical properties of biologic molecules antibodies bispecific antibodies antibody drug conjugates and genetic medicine modalities and identify liabilities that may impact drug development. - Enable automation and high-throughput screening of discovery candidate molecules. - Execute experimental protocols collect results and perform data analysis independently. - Maintain excellent documentation of work including electronic lab notebook and protocols. - Prepare and deliver concise scientific presentations of experimental results. - Oversee maintenance of key laboratory equipment and routine laboratory operations. - Build strong relationships with other team members and across groups. - Understand and adhere to corporate standards regarding code of conduct safety and documentation compliance. Qualifications: - BS or MS in Biochemistry Biology Chemistry or equivalent e.g. Chemical Engineering Pharmaceutical Sciences with 3 BS or 1 years MS biopharmaceutical industry experience preferred. - Hands-on experience in protein biochemical and biophysical characterization. Experience with diverse biologic formats desired. - Detailed knowledge of protein structure biophysical characterization and formulation screening. - Experience in protein biophysical and biochemical characterization techniques including chromatography size-exclusion ion exchange and hydrophobic interaction chromatography differential scanning calorimetry fluorimetry dynamic light scattering UV-VIS and fluorescence spectroscopy imaged capillary isoelectric focusing capillary electrophoresis particle and viscosity measurements. Must be willing and able to learn new technologies as needed. - Prior experience in high-throughput automation and mass spectrometry would be beneficial. - Demonstrated track record of independent thinking creativity and scientific accomplishment. - Highly responsible and self-motivated. Skills to plan and conduct experiments with high quality and timely deliverables. Able to perform data analysis using MS Excel GraphPad. - Team player with excellent collaboration and communication skills. If interested, please reach out directly to Lindsee Allienello at lallienello @ actalentservices.com Pay and Benefits The pay range for this position is $40.00 - $45.00/hr. Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: • Medical, dental & vision• Critical Illness, Accident, and Hospital• 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available• Life Insurance (Voluntary Life & AD&D for the employee and dependents)• Short and long-term disability• Health Spending Account (HSA)• Transportation benefits• Employee Assistance Program• Time Off/Leave (PTO, Vacation or Sick Leave) Workplace Type This is a fully onsite position in Worcester,MA. Application Deadline This position is anticipated to close on Feb 28, 2025. About Actalent Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. Diversity, Equity & Inclusion At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I are embedded into our culture through: + Hiring diverse talent + Maintaining an inclusive environment through persistent self-reflection + Building a culture of care, engagement, and recognition with clear outcomes + Ensuring growth opportunities for our people The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law. If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com (%20actalentaccommodation@actalentservices.com) for other accommodation options.
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