Scientist - Molecular Biology, Novel Expression Systems
Merck
**Job Description**
The Novel Expression Systems (NES) team is seeking a Scientist with experience in strain engineering and molecular biology. Our team is part of the Continuous & Expression Technologies group within the Process Research & Development Enabling Technologies organization. We are tasked with introducing and advancing expression systems across a range of organisms that will be applied to discovery and development of novel biologics and vaccines, as well as to our engineered enzymes. Our all-modality team works closely with scientists across our company to advance science and technologies with the goal of improving human health.
As a member of the Strain Engineering team in Novel Expression System group, the applicant will serve as an individual scientific contributor as part of a team responsible for strain construction and optimization of various expression systems for enzymes, vaccines, and other bioproducts. The candidate is also expected to carry out collaborative research supporting the implementation of these methodologies which involves conceiving, designing, and executing molecular biology experiments. A successful candidate should also have excellent interpersonal, communication and collaboration skills and maintain a focused attention on laboratory safety for everyone on the team.
**Responsibilities include but are not limited to:**
+ With medium to minimal supervision, design, conduct experiments for strain engineering and optimization with primary focus on eukaryotic hosts such as yeast.
+ Close collaborations with fermentation team within NES group and other cross function groups for operation and scientific support.
+ Contribute to a safe and compliant laboratory work environment.
**Education Minimum Requirement:**
+ BS with 2+ years of experience, or MS with relevant academic or thesis experience in molecular biology, genetics, biological engineering, biotechnology, biological science, microbiology, or related field.
**Required Experience and Skills:**
+ Hands-on experience in basic techniques in molecular biology.
+ Experience with plasmid construction and strain engineering.
+ Experience with typical analytical methodologies in molecular biology.
+ Technical knowledge and know-hows in microbial cultivation.
+ Well-developed organizational, record-keeping, and problem-solving skills.
**Preferred Experience and Skills:**
+ Experience with both prokaryotic and eukaryotic (preferably yeast) expression systems
+ Knowledge and experience in strain engineering and gene editing tools, such as CRISPR
+ Experience with statistical data analysis tools, design of experiments and data pipeline for visualization
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**U.S. Hybrid Work Model**
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
**San Francisco Residents Only:** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
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Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
**Employee Status:**
Regular
**Relocation:**
Domestic
**VISA Sponsorship:**
No
**Travel Requirements:**
10%
**Flexible Work Arrangements:**
Not Applicable
**Shift:**
1st - Day
**Valid Driving License:**
No
**Hazardous Material(s):**
N/A
**Job Posting End Date:**
02/4/2025
***A job posting is effective until 11:59:59PM on the day** **BEFORE** **the listed job posting end date. Please ensure you apply to a job posting no later than the day** **BEFORE** **the job posting end date.**
**Requisition ID:** R332464
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