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The Position

In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet medical needs. At pRED, we are united by our mission to transform science into innovative therapeutics. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to develop extraordinary life-changing innovation at speed.

The position is located in the Lead Identification department, within the Large Molecule Research unit  of pRED, which is responsible for the generation, identification and optimization of fit-for-purpose protein therapeutics. We closely collaborate with therapeutic areas and other global functions to discover next generation biotherapeutics.  

Job mission

We are offering an outstanding opportunity for an experienced (Senior) Associate to work with a highly engaged team of molecular biology, biochemistry, and display technologies specialists using an outstanding variety of state-of-the art technologies. You will be responsible for the in vitro discovery, characterization and engineering of antibody-based therapeutic molecules , as well as methods optimization and implementation. 

Your impact

Your main focus will be the discovery and optimization of therapeutic proteins 

This will include the cloning of antibody libraries, manual and automated ribosomal, phage or yeast display selections and high throughput screening

Promising candidates will be expressed, purified and characterized by a variety of methods with a particular focus on Surface Plasmon Resonance (SPR)

This will be followed by optimization using directed evolution and data-driven protein engineering

Furthermore, you will have the opportunity to collaborate with multiple internal and external partners.  

Your profile

You thrive in and are dedicated to establishing a culture of mutual support, cross-training, continuous learning and self-organization to meet project and functional goals. Furthermore, you thrive in a dynamic, inclusive environment that gives you full accountability for your own contributions and development. You know how to prioritize, how to create clarity and focus. 

Your experience in drug discovery, in vitro display methods as well as state of the art biochemistry enables you to support our technology and portfolio projects. 

You have a keen interest in protein engineering and display technologies as well as in working with IT systems and (semi)-automated platforms. 

For this position you hold a Bachelor- or Master's degree (FH) with relevant initial professional experience or an equivalent education with several years of professional experience.

You are resourceful and flexible in problem solving and in working in a collaborative and inclusive manner with strong oral and written communication skills.

This position is fix-termed to 2 years.

Your application

Please upload  your current resume and your latest certificates.

We are looking forward to your application!

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Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche at Penzberg, near Munich, employs more than 7,000 people. The site is one of the largest biotechnology centers in Europe and the only Roche site with research, development and production for both Pharmaceuticals and Diagnostics under one roof. From your beginning with Roche, our motivated team will welcome and support you. Numerous opportunities for personal development, flexible work hours, attractive compensation packages and special family assistance programs are available.

Roche is an Equal Opportunity Employer.