Look for more than answers.

At Quest, we are on a continuous journey of discovery and development. It’s this attitude that has made us an industry leader and the #1 Diagnostic Lab in the US. For those joining us, we offer exciting and fast-moving career opportunities where you can affect change at a rate unheard of in many organizations of our size and scope. While we invest in and develop technology to drive our innovations, our ongoing success relies on our people.

Quest Diagnostics Specialty Genetics products provide specific answers that clinicians need to deliver the appropriate diagnostic and prognostic care to their patients. You will work for the world leader in the industry, with a career where you will have the opportunity to collaborate and affect change while expanding your leadership skills and technical knowledge. You can make a real impact in a market that is growing and developing. 

As a Senior Bioinformatics Engineer, you will work for the world leader in the industry, with a career where you will have the opportunity to collaborate and affect change while expanding your leadership skills and technical knowledge. You can make a real impact in a market that is growing and developing.

This position is in our Operations group, part of the Research and Development organization, in Advanced Diagnostics based in Lewisville, TX. The role is specific to genetic testing in a highly regulated CAP/CLIA laboratory environment using short and long-read sequencing as the basis of evidence.  The right candidate will know how to balance innovation and standards with a practical understanding of when each is appropriate.  The Operations group supports, hones, and executes the processes defined by our Engineering group with emphasis in compliance and continuous improvement.  Though coupled tightly to regulation through standards in validation, documentation, and data retention, the group is an integral part of the development cycle of our analysis workflows and visualization.  

This position is intended to be near-site / hybrid with the intention of working on-site 2-3 days per week in our Lewisville, TX lab, and, if needed, provide rotating weekend coverage among a team of 5-6.

Execute and improve sequence analysis workflows and automationTrack, troubleshoot and mitigate issues encountered in processing production samplesDevelop new software applications or customize existing applications to meet specific scientific project needs.Plan and develop solutions to recurring issues to be merged back into development branch maintained by the Engineering groupDevelop and present web-based results and dashboards for clinical geneticists, medical directors and operations lab personnel staff, ensuring transparency and clarity in processes.Generate, wrangle, merge and glean information from varied and complex data setsImplement RESTful APIs to various systems including LIMS, AWS job runners and other systems necessary for data processing and executionPerform validation, testing, and production deployment in pursuit of systems to standardize processes across all Quest Diagnostics genetic testing labsSupport production day-to-day operations and on-call off hoursMaintain production documentation for compliance and supportability of all bioinformatics processes in production environmentProduce charts and visualization in dashboards, reporting and in support of data driven hypothesesPerform validations, formal testing, and deployment schemes to production systemsPerform validations, formal testing, and deployment schemes to production systemsPerform LIS support duties (maintain database for user, tests, clients….)Support interface integrating and testing projectsBe an active team player and support the groupExcellent analytical, troubleshooting and problem-solving abilities. Proficient in diagnosing and providing solutions for bugs and issues.Support On-call rotations as needed.
7 years experience using formal programming and scripting languages7 years experience working on a Linux command-line to process, parse, and merge varied data sets3 years experience working with web services and implementing API communications (REST, SOAP, etc.)3 years experience in a distributed HPC environment (cluster, cloud)Experience developing production grade software both supportable and extensibleExperience with source control in a development, testing, and production environmentAutomated testing experience: CI/CD experience preferredKnowledge of CAP documentation requirements a plusCurrent tech stack experience is a plus:Programming Languages: Python, PERL, Groovy, JavaScriptFrameworks: Python Celery, Python Flask, React Native, BootstrapEnvironments: R Statistical Language, iPython, JupyterVisualization: Plotly, matplot lib, ggplot2/tidyverse, Tableau, d3.jsDatabase: SQL (e.g., PostgresSQL, MySQL), MongoDBCloud Computing: AWS EC2 and serverless, DNAnexusInfrastructure management: TerraformPipeline Workflow Manager: NextflowSource Control: GitCI/CD: Gitlab/GitHubContainerizing: Docker

Education:
Bachelor’s Degree Required
Master’s Degree or PhD Preferred

Equal Opportunity Employer: Race/Color/Sex/Sexual Orientation/Gender Identity/Religion/National Origin/Disability/Vets