Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC® Discovery Engine platform to engineer proteolysis targeting chimeras, or PROTAC® targeted protein degraders, that are designed to harness the body’s own natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins.

In addition to its robust preclinical pipeline of PROTAC protein degraders against validated and “undruggable” targets, the company has three investigational clinical-stage programs currently enrolling: vepdegestrant for the treatment of patients with locally advanced or metastatic ER+/HER2- breast cancer; ARV-102 for the treatment of patients with neurodegenerative disorders, and ARV-393 for the treatment of patients with relapsed/refractory non-Hodgkin Lymphoma and potentially other lymphomas.

In April 2024, Arvinas entered into a transaction with Novartis, including a global license agreement for the development and commercialization of the clinical stage PROTAC® androgen receptor protein degrader ARV-766 for the treatment of prostate cancer. The transaction closed in May 2024.

#TeamArvinas is made up of approximately 450 passionate and curious employees, whose diverse thoughts and perspectives are highly valued. Arvinas employees embrace the freedom to pursue innovation, think creatively, and give back. They are driven by the company’s values and mission – to improve the lives of patients with serious diseases by pioneering therapies created with our revolutionary PROTAC® protein degradation platform. We’re really excited about the work we’re doing inside and outside of Arvinas, and think you will be, too. But don’t just take our word for it – learn more about life at Arvinas and what employees have to say.

For more information, please visit www.arvinas.com. 

  

Position Summary

The position leads project management for 2-3 Development programs portfolio and supports assets establishing a plan from CCN to FIH and beyond. The role will be a player coach and will lead project management for a few programs and mentor and guide other junior colleagues on PM best practices. The role will oversee establishing a team structure, resources, key stage gates, budgets, risks and plans for the assigned assets. We currently anticipate this role to serve as the PM lead for 2 Oncology assets. The role will also support and drive building out key infrastructure and processes for Project Management as a key leader in the organization interfacing with other aspects of the organization including Planning, Discovery and CMC when appropriate.

This position reports to the Head of Enterprise Project Management and Governance and will be a hybrid role in New Haven, CT.

 

Principal Responsibilities

Key responsibilities of this role include, but are not limited to:

Partners with Development Team Leadership and teams in managing an integrated view about the assets, their key milestones, goals, budgets, risks, and plans. Partners with assigned planner and asset teams in creating and maintaining integrated cross-functional program plans, including development and assessment of scenarios and options, decision criteria, and internal and external cross-functional communication and stakeholder management strategies. Partners with Discovery teams and their leadership to support Clinical transition planning, engaging with key Development stakeholders to support downstream planning and engagement. Challenges teams to think about and anticipate risks, proactively manage risks and develop mitigation strategies. Manages core team and sub-team meetings as appropriate and accurately incorporates functional area objectives into overall development plan. Drives and leads adherence to Arvinas Drug Development and governance processes, including delivery of timely and quality project team and/or sub team deliverables. Ensures alignment of asset integrated development plan and corporate strategic and operational plans. Drives decision making and asset team deliverables cross functionally and is a key contributor to annual planning processes such as budgeting, forecasting, BOD presentations, IDP refreshes Adheres to Project Management Standards and Deliverables Develops and maintains integrated program budget and forecasts for the assets in collaboration with Asset Team leaders, Cross-functional team members and Finance Develop and maintain high performing teams and coach/mentor project managers supporting individual teams Ability to manage multiple high priority projects including key cross functional process efforts that further strengthen the portfolio. Seeks participation in corporate initiatives outside the scope of the assets Ability to conduct process analysis and develop and implement plans Ensure effective communication with external stakeholders and collaborative partners Willing to identify, develop and/or implement forward thinking research and development initiatives, processes, or tools to support company growth and transformation Thought leader with the ability to provide creative solutions, with the support of the PM team, and pragmatic delivery of project

 Qualifications

15+ years in the pharmaceutical industry in roles associated with drug development 10+ years supporting cross-functional early and late-stage drug development teams in core function Drug development knowledge, Oncology experience preferred, with basic to strong understanding of other functions relevant to the position which may include: research, toxicology, clinical pharmacology, clinical, manufacturing, and regulatory. Must be able to work independently and collaboratively in a fast-paced, matrixed, team environment consisting of internal and external team members. Superior communication and interpersonal skills; effective interaction with cross functional team members. Experienced in managing multiple initiatives while working in a fast paced and dynamic environment. Demonstrated planning, organization and time management skills including the ability to support and prioritize multiple projects. Ability to adapt quickly to changing priorities Excellent problem-solving skills and the ability to adapt to changing priorities and deadlines. Highly motivated, self-starter able to work with minimal supervision and direction Excellent attention to detail Skilled in managing multi-disciplinary teams both internally and externally Proficiency with Project Management related and Microsoft Office Software Programs. Arvinas will not be providing VISA sponsorship for this position. You must have the ability to work without a need for a current or future VISA sponsorship. The duties of this role are generally conducted in a combination of company office and home office environments. Employees must be able, with or without an accommodation to lift/carry 15/30 pounds unassisted/assisted; work comfortable in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving, analysis and dialogue; collaborate with others; maintain general availability during standard business hours.

Education

Bachelor’s degree in Life Sciences or Pharmacy or higher.

 

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity employer