At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. **Overview:** At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism. **Position Summary:** The Discovery Biology team will be part of a multi-disciplinary effort focused on bringing forward innovative cancer drug therapies. The Senior Director will be responsible for leading a research team to identify the next generation of cancer therapeutics. Experience in systems biology, molecular and cell biology, and/or chemical biology is required. The Senior Director will drive discovery strategy of early validation of oncology targets through close collaborations with other discovery and translational functions. **Responsibilities:** + Lead cross-functional teams that will be responsible for novel small and large molecule target discovery and validation, including Discovery Biology team members in SSF and other Lilly research sites + Supervise and mentor PhD and non-PhD scientists engaged in target identification and validation to think deeply and work creatively while delivering excellent scientific results and insights to the project teams and their colleagues + Develop and implement strategies that will enable Discovery Biology team members to continually advance internal drug development efforts through our discovery, clinical and research programs + Innovate technologies and methods to advance our discovery projects + Engage leaders across Lilly to identify, credential, and advance new targets and serve as a liaison for the Discovery Biology team and the company at large + Provide strategic input, in partnership with Discovery leadership, into computational and experimental validation for key new targets + Contribute to due diligence evaluation of external opportunities, participate in KOL engagement around target programs, and help identify academic and industry partnerships and collaboration. **Basic Requirements** : + PhD in systems biology, molecular and cellular biology, chemical biology, or related field + Minimum of 8-10 years research experience following post-doctoral training with prior experience in target discovery/credentialing and cancer biology in the biotech or pharma setting + Extensive experience in areas of cancer biology and cancer genomics + Experience with incorporating massively parallel genetic screening data in target identification and credentialing workflow (i.e. CRISPR screens) + Demonstrated evidence for the ability to partner with computational biologists to leverage systems-scale datasets + Experience in leading PhD level scientists + Outstanding communication, writing, and presentation skills is a must + Highly organized with excellent analytical, documentation and multi-tasking skills + Provide strategic input to target identification and validation strategy to leadership team **Additional Preferences:** + Experience with early clinical trial studies and the development and implementation of pharmacodynamic and patient selection biomarker assays + Experience working with external CROs to optimize internal/external resources **Additional Information:** **Physical Demands/Travel:** The physical demands of this job are consistent with a lab environment **.** _The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job._ **Work Environment:** This position’s work environment is in a Laboratory. _The_ _work_ _environment_ _characteristics_ _described_ _here_ _are_ _representative of those an employee encounters while performing the essential functions of this job._ _*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions._ Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $166,500 - $244,200 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. \#WeAreLilly