**HOW MIGHT YOU DEFY IMAGINATION?** You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role. **Senior Manufacturing Systems Engineer** **Live** **What you will do** Let’s do this! Let’s change the world! As a senior member of the Manufacturing & Clinical Supply – Facilities & Engineering (MCS-F&E) Automation team you will ensure successful Drug Substance manufacturing and innovation in the Pilot Plant Network. You will be trusted to exhibit solid performance in a range of professional and technical skills that ensure flawless execution of production and drive next generation technology development in the biopharmaceutical manufacturing environment. To successfully navigate this dynamic role, one must develop a mastery of automation controls, equipment process knowledge, analytical problem-solving techniques, critical thinking, project management, lifecycle management, and execution excellence. **Primary Responsibilities:** + Day-to-day operational support including: rotational 24x7 on-call support + Develop and maintain process control automation solutions using DeltaV Distributed Control System (DCS). + Lead technical root cause analysis, incident investigations, and troubleshooting on process control issues related to plant operations. + Investigate and implement new manufacturing or process automation technologies. + Identify and implement continuous improvement projects that align with Amgen initiatives around Safety, Reliability, Efficiency and Environmental sustainability. + Maintain automation system health and resiliency via cybersecurity, data integrity, and preventative maintenance in alignment with the latest Amgen and industry standards + Refine or create business processes and procedures including departmental Standard Operating Procedures (SOP). **Win** **What we expect of you** We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications. **Basic Qualifications:** + High school diploma / GED and 10 years of Manufacturing Automation Engineering experience OR + Associate’s degree and 8 years of Manufacturing Automation Engineering experience OR + Bachelor’s degree and 4 years of Manufacturing Automation Engineering experience OR + Master’s degree and 2 years of Manufacturing Automation Engineering experience OR + Doctorate degree **Preferred Qualifications:** + 3+ years’ combined experience with the following: + Emerson DeltaV DCS system with batch control and recipe management + System Integration using OPC, Profibus, EIP, WIOC, and DeviceNet technologies. + DeltaV Virtual infrastructure configuration, management, and troubleshooting + Mastery of hands-on troubleshooting of complex process automation systems; to be carried out in partnership with adjacent support teams, e.g. plant engineering, instrumentation. + Background in programming, code design, manufacturing process controls, and biopharmaceutical equipment instrumentation. + Direct experience with biopharmaceutical equipment automation design, process control engineering, and troubleshooting. Example equipment: bioreactors, chromatography skids. + Experience with Capital Project Lifecycle Management: conceptual design, scope and cost estimate development, business case development, detailed design, engineering and validation documentation, and project execution. + Familiarity with drug substance manufacturing at the unit operation level. + Strong leadership, technical writing, and communication/presentation skills. + Independent, self-motivated, organized, and able to drive projects to desired outcome. + Team player that leverages collaboration for effective decision-making and execution. + Mentor with a base desire to help team members grow and thrive for the collective good. **Thrive** **What you can expect of us** As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: + Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. + A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan + Stock-based long-term incentives + Award-winning time-off plans and bi-annual company-wide shutdowns + Flexible work models, including remote work arrangements, where possible **Apply now** **for a career that defies imagination** Objects in your future are closer than they appear. Join us. **careers.amgen.com** Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.