We are seeking a Senior Principal Scientist with a focus in Ophthalmology to join our Clinical Imaging team. You will conceptualize, support, execute, operationalize and optimize complex early- to late-phase ophthalmology clinical trials where imaging plays a central role. Work closely with Regeneron clinical, preclinical and external partners, with emphasis on delivery of high quality imaging data and development of innovative imaging-based biomarkers across ophthalmic modalities and indications. As a Senior Principal Scientist in Clinical Imaging, a typical day may include the following: + Collaborate closely with Research colleagues in Ophthalmology to develop and qualify imaging biomarkers with a view toward clinical translation + Collaborate with Regeneron clinical teams as imaging subject matter expert to ensure optimal design and execution of imaging biomarker strategy related to study endpoints, including development of protocols, imaging manuals, imaging charters and statistical analysis plans, and be the main clinical team collaborate with imaging Clinical Research Organizations (CROs) ensuring flawless conduct and data integrity of study’s imaging components + Collaborate closely with different functions such as Regeneron Genetics Center, Imaging Sciences, Precision Medicine etc. and work on development and execution of joint image analyses projects, including novel imaging biomarker development + Collaborate closely with external vendors, investigators and site personnel and Clinical operations teams to ensure the appropriate selection of Imaging equipment and parameters for image acquisition and pre- and on-study QC/calibration and standardization + Oversee image analysis and interpretation of results and work closely with colleagues to oversee the development of study reports and publications as appropriate + Support regulatory submission packages with the appropriate original content and documentation **This may be for you if:** + Work efficiently within a fast-paced, collaborative environment + Come up with new and outstanding ideas that move solutions forward. + Possess a broad knowledge and perspective and are future oriented. + Desire to make a broader impact on developing medicines for patients with serious diseases To be considered for this you will need PhD with 8+ years of demonstrated ability in Ophthalmology Clinical Imaging. You should possess extensive familiarity with ocular imaging modalities such as OCT, FA, FP etc. We are seeking a strong understanding of ocular imaging file formats and analysis methods. We need demonstrated ability in the development and validation of ocular imaging biomarkers. Should also have experience in creating and managing imaging protocols, manuals, and charters, and be proficient in statistical analysis plans related to imaging endpoints. Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels! Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business. For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location. Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc. **Salary Range (annually)** $145,400.00 - $237,200.00