Kelly® Science & Clinical is seeking a Senior Research Associate, Proteomics for a direct hire opportunity with one of our clients, an early stage transcription factor therapeutics biotechnology company in the Seattle area. If you’re passionate about bringing the latest scientific discoveries to life and are ready to take the next step in your career, trust The Experts at Hiring Experts. **Position Title:** Senior Research Associate, LC/MS Proteomics **Position type:** Direct hire **Workplace:** Onsite in the Greater Seattle area **Salary:** $80,000-100,000 **Overview** We are seeking a full-time Senior Research Associate, Proteomics. The role involves developing, optimizing, and executing mass spectrometry-based workflows for proteomics research in a preclinical biotech setting. **Responsibilities** + LC-MS Operation & Maintenance: Operate, maintain, and troubleshoot mass spectrometers and liquid chromatography systems. + Sample Preparation: Perform protein extraction, digestion, and clean-up for LC-MS/MS analysis. + Proteomics Analysis: Conduct DIA, DDA, and PRM proteomics experiments. + Method Development: Develop and optimize proteomics methods for sample preparation and LC-MS. + Data Analysis & Interpretation: Analyze and interpret proteomics data using software and bioinformatics tools. + Collaborative Research: Collaborate with cross-functional teams on experiment design and execution. + Documentation & Reporting: Maintain detailed records, analyze data, and present findings at meetings and conferences. **Qualifications** + Education & Experience: BS in biology, chemistry, or related field with 3+ years of experience; or MS with 1+ year of experience in proteomics and mass spectrometry. + Mass Spectrometry: Hands-on experience with LC-MS/MS systems (e.g., Orbitrap, Q-TOF), including operation and troubleshooting. + Sample Preparation: Expertise in cell culture, protein extraction, digestion, and peptide clean-up. + Data Analysis Tools: Proficiency with proteomics software (e.g., Skyline) and data analysis. + Technical Problem-Solving: Proven ability to troubleshoot instruments and optimize methods. + Communication Skills: Strong verbal and written communication skills for presenting data. Preferred: + LC-MS Method Development: Experience with DDA, DIA, or PRM method development. + Automation Skills: Understanding of automated sample preparation and high-throughput workflows. + Bioinformatics Integration: Basic coding skills (R or Python) for data analysis and presentation. **What happens next:** Once you apply, you’ll proceed to the next steps if your skills and experience look like a good fit. But don’t worry – even if this position doesn’t work out, you’re still in our network. That means our team of expert Science & Clinical recruiters will have access to your profile, making your opportunities limitless. \#P1 As part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work-related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, a legal plan, and short-term disability. As a Kelly employee, you will have access to a retirement savings plan, service bonus and holiday pay plans (earn up to eight paid holidays per benefit year), and a transit spending account. In addition, employees are entitled to earn paid sick leave under the applicable state or local plan. Click here (https://www.mykelly.com/help-support-working-with-kelly-us/#Benefits) for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community. Why Kelly ® Science & Clinical? Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire industry experts just like you. Our team creates expert talent solutions to solve the world’s most critical challenges. Every day, we match science professionals with dream jobs that fit their skills, interests, and career goals—it’s the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background and education in science, so we know a thing or two about the science market and how to get your expertise noticed. About Kelly Work changes everything. And at Kelly, we’re obsessed with where it can take you. To us, it’s about more than simply accepting your next job opportunity. It’s the fuel that powers every next step of your life. It’s the ripple effect that changes and improves everything for your family, your community, and the world. Which is why, here at Kelly, we are dedicated to providing you with limitless opportunities to enrich your life—just ask the 300,000 people we employ each year. Kelly Services is proud to be an Equal Employment Opportunity and Affirmative Action employer. We welcome, value, and embrace diversity at all levels and are committed to building a team that is inclusive of a variety of backgrounds, communities, perspectives, and abilities. At Kelly, we believe that the more inclusive we are, the better services we can provide. Requests for accommodation related to our application process can be directed to Kelly’s Human Resource Knowledge Center. Kelly complies with the requirements of California’s state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. Kelly participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S. Kelly Services is proud to be an Equal Employment Opportunity and Affirmative Action employer. We welcome, value, and embrace diversity at all levels and are committed to building a team that is inclusive of a variety of backgrounds, communities, perspectives, and abilities. At Kelly, we believe that the more inclusive we are, the better services we can provide. Requests for accommodation related to our application process can be directed to Kelly’s Human Resource Knowledge Center. Kelly complies with the requirements of California’s state and local Fair Chance laws. A conviction does not automatically bar individuals from employment.