**Why Mayo Clinic** Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans (https://jobs.mayoclinic.org/benefits/) – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic. You’ll thrive in an environment that supports innovation, is committed to ending racism and supporting diversity, equity and inclusion, and provides the resources you need to succeed. **Responsibilities** The Sammarco lab, in the Department of Orthopedics, focuses on limb regeneration after traumatic injury, investigating mechanisms underlying impaired regeneration and identifying therapeutics to activate latent regenerative abilities or improve the integration of prosthetics. The overall goal is to improve quality of life for people with limb loss or limb differences. Dr. Sammarco and her team in the Limb and Musculoskeletal Regenerative Research Laboratory use a mouse model of digit tip amputation to understand the complex interactions of a multi-tissue regenerative system and identify the mechanisms that drive cell differentiation and patterning during the regenerative process. Current projects focus on 1) mitochondrial remodeling and metabolism during limb regeneration and patterning, 2) the role of sensory nerves in bone and soft tissue regeneration, and 3) the impact of inflammation during regenerative healing and fibrotic scarring. The Senior Research Tech would support ongoing bench and animal work within the lab related to regeneration. Duties would include routine molecular bench work combined with use of animal models (animal handling, injections, surgeries, sample collection) as well as downstream processing (histology, flow cytometry, cell culture) under supervision of the PI. Candidate should be highly goal and detail oriented and have strong teamwork skills. Training will be provided on many in-lab techniques but previous experience working with mice and some molecular technique is highly preferred. Independently sets up and performs experiments and procedures in support of lab goals and grant commitments (e.g. assays, cell/tissue culture, animal studies, etc.). Contributes to the planning, design and modification of studies and experiments in the research lab setting. Monitors results, reports unusual outcomes and suggests modifications. Collects, enters, summarizes, and analyzes data. May oversee and assist with the training of residents, fellows and temporary lab personnel in lab techniques. Works with minimal supervision and performs assignments independently as discussed and approved by Principal Investigator. Prior experience in all techniques is not required - personnel will be fully trained in all techniques within the lab. **Qualifications** Qualifications: Requires bachelor's degree in biology, chemistry, or other relevant science with 4 years of research laboratory experience. Master's degree in biology, chemistry, or other relevant science preferred. **Additional Experience and/or Preferred Qualifications:** Master’s degree in biology, chemistry, or other relevant science preferred. Mouse breeding colony and handling experience is a plus. Prior exposure to molecular techniques such as immunohistochemistry, cell culture assays, and qPCR is helpful but not necessary. Familiarity with GraphPad and Adobe Illustrator is helpful but not necessary. Personnel will be fully trained in all additional techniques within the lab. **Exemption Status** Exempt **Compensation Detail** Education, experience and tenure may be considered along with internal equity when job offers are extended.; $64,500- 96,824 annually. **Benefits Eligible** Yes **Schedule** Full Time **Hours/Pay Period** 80 **Schedule Details** M-F 8-5 **Weekend Schedule** none **International Assignment** No **Site Description** Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. (https://jobs.mayoclinic.org/alllocations) **Affirmative Action and Equal Opportunity Employer** As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available. **Recruiter** Jill Squier **Equal opportunity** As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.