Job Title: Scientist/Senior Scientist
Location: Seattle, WA - Hybrid
Compensation: $62.00 - $78.45/hr
Type: Contract, Potential for extension or conversion to permanent
 
Responsibilities Work collaboratively with Integrated Attribute Sciences Team members to identify, prioritize and support immediate IAS team goals and deliverables requiring the application of in depth drug product and starting materials characterization technologies and platforms for execution Design, optimize and execute in-depth characterization experiments of cell therapy starting materials and drug products to answer high priority targeted questions (such as investigation of product mechanisms of action MoA, responses agency’s information requests, manufacturing investigations, etc) Perform and manage characterization method and instrument troubleshooting Generate in depth characterization data packages and conclusions of pipeline allogeneic starting material and CAR T cell products to enable immediate IAS team deliverables leveraging cutting edge phenotypic, functional, metabolic, gene expression profiling tools and platforms, etc. Collaborate with members of the Attribute Sciences Team to identify, prioritize, and develop novel/next generation in Analytical Platforms and Technologies to interrogate cell therapy product function and MoA Present experimental findings and project updates at cross-functional team meetings and to company leadership Serve as T cell biology subject matter expert in multidisciplinary team setting, that includes non-clinical, clinical, regulatory, and CMC functions Author, review, and approve technical documents, including methods, protocols, reports, and SOPs  
Requirements Expertise in cellular and/or molecular immunology. Prior experience with cell therapy products (i.e. autologous or allogeneic T/CAR T cells, NK cells, HSC and/or iPSC) will be prioritized Experience with routine and next generation analytical platforms for the characterization of T cell phenotype, differentiation, and function (i.e. cell-based immunoassays, cytokine/proteome analysis platforms, in vitro live imaging systems, conventional and spectral flow cytometry, metabolic profiling, CRISPR and gene editing, transcriptome and proteome profiling, etc) Experience with data analysis and visualization software (Flowjo, OMIQ, JMP, EXCEL, etc.) and/or coding-based analysis (R, Python, etc.) Independence in experimental design, data analysis, interpretation, and presentation Ability to work in a high paced, cross-functional team environment, meet deadlines, & prioritize work on multiple projects Attention to detail and excellent interpersonal, written and verbal communication skills
Preferred Qualifications: Experience with big/omic data analysis will be prioritized Track record of successful internal and/or external scientific collaborations Experience in managing and/or mentoring more junior scientists
Education Scientist Level: PhD and 0-3 years; MS and 8+ years; BS and 10+ years in Immunology, Cell Biology, Bioengineering, or relevant discipline Senior Scientist level: PhD and 3+ years; MS and 10+ years; BS and 12+ years in Immunology, Cell Biology, Bioengineering, or relevant discipline

Benefits
System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan. 
 

System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.