Minneapolis, MN, USA
74 days ago
Senior Scientist - Cell and Gene Therapy

By joining Bio-Techne, you’ll join a company with a powerful and positive purpose of enabling cutting-edge research in Life Sciences and Clinical Diagnostics. Bio-Techne, and all of its brands, provides tools for researchers to further treat and prevent disease worldwide.

Position Summary:

The Cell and Gene Therapy Solutions Senior Scientist will be part of a dynamic team responsible for the design and development of novel products and applications used in regenerative medicine workflows. They will be uniquely positioned to utilize the vast content of Bio-Techne products and collaborate across the business to maximize the value of our Cell and Gene Therapy portfolio.  Responsibilities include developing tools for expansion, differentiation, and characterization of stem cell derived models. Experience culturing stem cells (e.g. iPSC, ESC, MSC or adult stem cells) is required.

We are seeking a highly skilled and experienced stem cell scientist. The successful candidate will play a critical role in developing and improving human pluripotent stem cell (hPSC)-based differentiation and characterization methods for clinical applications.  

Key Responsibilities:

Identify and develop products, workflows and key culture optimizations (i.e. expansion, differentiation, and characterization) for stem cell-based therapy research and manufacturingDevelop and optimize robust and reproducible cell differentiation protocols, analytical methods, and other processes needed to convert human induced pluripotent stem cells (iPSCs) into cellular products and therapeutics.Lead core teams and collaborate with cross-functional teams to formulate cell differentiation reagents and protocols for different iPSC-derived cell typesServe as a subject matter expert for new product initiatives, including process development, closed systems and protocol scaling programsDevelop cell-based, biochemical, and/or molecular assays to characterize the identity and physiology of stem cell-derived differentiated cellsPlan and perform experiments, analyze data, and generate presentations to inform project progress to wider department and leadershipProvide substantial, high-quality contributions to projects by working independently, communicating effectively within cross-functional team and leverage available expertise and support across the organizationContribute to corporate scientific activities/roadmaps/strategyApply scientific methods and process design principles to improve development, manufacturing and quality control processes Author documentation including standard operating procedures (including Manufacturing and QC) for RUO and GMP products, design verification and validation procedures, and technical reports to support lab operation, development initiatives, and product investigationsCreate talks and presentations to clearly communicate and break down complex scientific topics to technical and non-technical audiences internally and externallyStay up-to-date with the latest scientific developments and market offerings in the fields of stem cell, organoids and regenerative medicineProvide subject matter expertise, mentorship and leadership to other scientists and research associates across department and the wider Bio-Techne team

Desired Qualifications and Experience:

Ph.D. in Biology, Chemistry, Biomedical engineering, Chemical Engineering, or related fieldMinimum of 2+ years post-Ph.D. experience, preference for industry-related experienceThe ideal candidate would have translational experienceSignificant technical expertise/scientific knowledge of autologous or allogeneic cell therapies or differentiation pathways  Extensive hands-on experience with pluripotent or adult stem cell culture including expansion and differentiation required. Fluorescent based microscopy and standard cell characterization assays (e.g. RT-PCR, flow cytometry, ELISA, or ICC) required. 3D culture experience including spheroid, organoid and high throughput assays or high content imaging experience strongly preferred. Gene editing and Biomaterials experience a plusPrior demonstrated experience developing and validating/verifying product workflows under design control using a requirements-driven, risk-based approach within the biotech industry or clinical laboratoryBe self-motivated, action oriented, highly collaborative and team focused, results driven with high levels of professionalism, responsibility and positive attitude.Possess a strong track record of independence, scientific productivity, and creative problem-solving

Why Join Bio-Techne:

We offer competitive wages along with extensive benefits for employees and their families.We invest in our employees’ financial futures through retirement programs and an employee stock purchase plan.We help our employees develop their careers through mentorship, promotional opportunities, training and development, internship programs, and more.We offer an international and diverse working environment, enriched by employee resource groups; volunteer and charity events; and employee events that build a culture of caring and belonging. We foster a culture of empowerment and innovation, where employees feel valued and encouraged to bring their new ideas to the table.

Bio-Techne is an E-Verify Employer in the United States.

Bio-Techne is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

To protect the interests of all, Bio-Techne will not accept unsolicited resumes from any source other than a candidate application. Any unsolicited resumes sent to Bio-Techne will be considered Bio-Techne property.

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