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Biochemistry & Molecular Biology has an exciting opportunity for a Senior Bioinformatics Analyst position. The incumbent is available within the Telonis lab at the Department of Biochemistry and Molecular Biology, University of Miami, Florida for a basic research project studying the role of gene architecture in regulating gene expression in normal physiology and in disease, including cancer. Our previous work has demonstrated that stem cells express genes of a specific architecture and retrotransposon content but as stem cells differentiate they express genes with a different underlying structure, particularly of the respective introns (BMC Biol 2021 19(1):60; Nat Commun 13(1):6524).

We are seeking a highly talented and motivated computer scientist to join the lab. The candidate should demonstrate expertise in software development, with emphasis in algorithms analyzing biological “omic” data, e.g. RNA-sequencing, ATAC-seq, HiC, ChIP-seq. Prior experience in machine learning (artificial intelligence, AI) is preferred but not required. It is expected that the candidate will have the ability to develop, curate and maintain novel AI-based computational pipelines or apply existing bioinformatic tools for biological discovery.

JOB FUNCTIONS

1. Develops and maintains next generation data analysis pipelines.

2. Assists in analysis pipeline and algorithms development and validation.

3. Extracts features of interest from data relating to specific biological questions.

4. Contributes to the development and maintenance of genomic and clinical databases.

5. Performs statistical and integrative data analysis on genomics and clinical data.

6. Supervises team members and other data analysts.

7. Establishes standard operating procedures, documentation, and scripts to generate custom reports.
8. Progresses material for bioinformatics tutorials and training courses.

9. Tests the characterization and integration of diverse third-party bioinformatics algorithms.

10. Adheres to University and unit-level policies and procedures and safeguards University assets.

This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.

CORE QUALIFICATIONS                                                                                                  

Bachelor’s Degree in relevant field; Masters in computer science, or bioinformatics- preferred.

Minimum 3 years of relevant experience

Department Specific Functions

Being responsible for the curation and analysis of “omic” biological data, including data from RNA-sequencing, DNA methylation, ChIP-seq, ATAC-seq, HiC experiments.

Development, maintaince and optimize computational software (“pipelines”) for the analysis and mining of “omic” biological data, considering factors like load time.

Developing and applying machine learning (Artificial Intelligence, AI) algorithms for answering biological questions on “omic” datasets.

Work with version control systems to manage the lab’s code repositories and facilitate team collaboration.

Assist with other lab members’ research and coding efforts, including code review to ensure code quality, performance and share knowledge.

Participate in scheduled lab meetings within the lab, department or with collaborators.

Evidence of scholarly ability (e.g. record of publication in peer-reviewed journals).

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The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.

UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

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