At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$158,250 - $275,000

The Biotechnology Discovery Research group at Lilly’s Biotechnology Center in San Diego discovers medicines that address significant unmet needs by integrating biology with innovative scientific capabilities in protein engineering and computational sciences.  In addition to our internal efforts, we collaborate with a broad network of external companies, partnering through our Catalyze360 external innovation program.  We are looking for a motivated scientific leader with large molecule discovery and protein engineering expertise and a strong ability to represent and manage teams to join us in making a difference for patients, partners and the communities we serve!  The successful candidate will oversee efforts to discover, design, and engineer protein therapeutics for desired biological function, potency, stability, developability, and low immunogenicity for external partners as part of our Catalyze360 program. There will be opportunities to engineer proteins and/or antibodies for cutting edge technologies including bi-/multi-specifics and targeted delivery of bioconjugates or nucleic acids to cells. The successful candidate will have strong scientific skills and broad knowledge, as well as the ability to manage key relationships with partners and internal stakeholders.

If you are a highly motivated teammate, with a passion for goal-oriented scientific research, with prior industry experience and external influence in protein engineering and possess a sound practical knowledge of molecular biology, structural biology, biological chemistry, immunology, and cell biology we urge you to join the Lilly Team today!

Responsibilities:

Work within scientific discovery and engineering team to facilitate external collaborative research projects.Discover and engineer first- or best-in-class biotherapeutics by integrating biology and a deep understanding of molecular properties Coordinate with business development, research, and external partners in design and execution of complex projects involving antibodies and other large molecules.Strong and effective communicator of progress on individual projects and broader programs internally and externally.Organize and present data to support decisions in cross-functional teams.Prepare, review, and sign off on technical documents and reports.Review the literature, attend meetings and conferences, and maintain an updated knowledge in the field.Contribute to the preparation of scientific products, such as presentations, writing reports, protocols when appropriate.

Basic Qualifications:

Ph.D. in biochemistry, biophysics, biological chemistry, structural biology, molecular biology or related fieldMinimum 5 years of relevant experience beyond education/postdoctoral training in a pharmaceutical, biotech, or research organization (10+ years desired)Excellent communication skills to drive positive internal and external interactions and relationships are critical 

Additional Skills/Preferences 

Knowledge of formats used for biologics including standard IgG, multispecifics, domain binders, and Fc engineering.Experience/knowledge of discovery and engineering platforms for biologics including transgenic mouse, bacteriophage, yeast display, mutagenesisExperience creating complex project plans in large molecule discovery and engineering.Ability to collaborate with internal and external partners in design and execution of projects.Expertise in molecular biology, protein characterization, NGS, lab automation/robotics, protein-protein interactions, protein conjugation, and protein structure prediction are desirable skills.Experience/knowledge of screening assays used in biologics discovery including ELISA, FACS, reporter assays, SPR, developability analysisStrong mentor and coach.  Commitment to foster diverse and inclusive environments.Creative problem-solver who can influence diverse teams to align on strategy and execution.Strong teammate and independent scientist ready to work effectively in a collaborative, fast-paced environment.Ability to drive close partnerships with cross-functional colleagues across geographies.Attention to detail and critical thinking.  Able to prioritize work and meet target timelines.Proficiency with Microsoft Office applications (Excel, Word, PowerPoint).  Proficiency with advanced scientific software (e.g., Spotfire, JMP, MOE) are a plus.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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