Description

Job Title:

Sr. Research Associate

Location:

San Diego, CA

Position type:

FLSA:

Full time

Non-Exempt

Department:

Research Biology

Strive to Bring a Profound Difference to our Patients

At Avidity Biosciences, we are passionate about the impact of every employee in realizing our vision of improving people’s lives by delivering a new class of RNA therapeutics. Avidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies. If you are a committed, solution-oriented thinker, join us in making a difference and become part of our growing culture that is integrated, collaborative, agile and focused on the needs of patients. 

Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs™). Utilizing its proprietary AOC platform, Avidity demonstrated the first-ever successful targeted delivery of RNA into muscle and is leading the field with clinical development programs for three rare muscle diseases: myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). Avidity is broadening the reach of AOCs with its advancing and expanding pipeline, including programs in cardiology and immunology through internal discovery efforts and key partnerships. Avidity is headquartered in San Diego, CA. For more information about our AOC platform, clinical development pipeline, and people, please visit www.aviditybiosciences.com and engage with us on LinkedIn and Twitter.

The Opportunity

We are seeking an experienced in vivo Biology Research Associate to characterize in vivo properties of novel therapeutic Antibody Oligonucleotide Conjugates that deliver nucleic acids. Previous experience handling rodents, various dosing routes, blood collection and tissue sample collection required. The associate will closely collaborate with colleagues in pre-clinical discovery and present scientific results to multidisciplinary teams and senior management.

What You Will Contribute

The candidate will be responsible for the execution of in vivo animal studies including functional studies addressing mobility and muscle strength, development of muscle/cardiac disease models, tumor model development, and pharmacokinetic PK /pharmacodynamics PD/ biomarker studies.

What We Seek

B.S. degree in the biological sciences with at least 3 years of relevant in vivo animal study experience  Experience with mouse muscle/cardiac disease models and evaluating muscle/cardiac function and structure/histology is highly preferred  Knowledge of laboratory mouse behavior, anatomy, and guiding principles for animal welfareHigh proficiency in animal handling, various dosing techniques (IV, SC, IP, RO, IM), bleeding techniques (RO, tail, Submental, cardiac), necropsy and micro dissection, and sample handling.  Mouse surgical experience, preferredDemonstrate strong skills in aseptic techniques, proper handling of protein biologics, and data collection and analysis. Proficient computer and data analysis/management skills - Microsoft Office Suite, Prism, and BenchlingStrong organizational skills and attention to detail, including the ability to manage several projects simultaneously. Demonstrated ability to work effectively with little to no supervision and in a fast-paced and dynamic environment with a diverse team of co-workers What We will Provide to You:The base salary range for this role is $80,000 - $90,000 ($38.47/hr. - $43.27/hr.). The final compensation will be commensurate with such factors as relevant experience, skillset, internal equity and market factors.Avidity offers competitive compensation and benefits which includes the opportunity for annual and spot bonuses, stock options and RSUs, as well as a 401(k) with an employer match. In addition, the comprehensive wellness program includes coverage for medical, dental, vision, and LTD, and four weeks of time off.A commitment to learning and development which includes a variety of programming internally developed by and for Avidity employees, opportunities for job-specific training offered by industry, and an education reimbursement program.

Avidity Biosciences

10578 Science Center Dr. Suite 125

San Diego, CA

92121

O: 858-401-7900

F: 858-401-7901

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