Site Name: USA - Pennsylvania - Upper Providence Posted Date: Oct 22 2024 Are you a driven analyst/chemist looking for an opportunity to work in cutting edge separation science? Do you have team leadership experience? Are you looking for a unique opportunity to diversify your skills across a broad range of analytical techniques and molecular modalities? We are seeking a highly motivated individual to lead our team of purification scientists working with and supporting GSK discovery chemistry at our Upper Providence R&D site. The UP purification group is a multidisciplinary team that works with project teams to progress the discovery and development of small molecules from hit identification through early development (non-GxP). This position will help to enable the effective partnership of chemistry teams from Medicinal and Development Chemistry with Analytical Chemistry. The successful applicant will join the Analytical Chemistry team, managing their own group and developing critical analytical and preparative LC, LC/MS and SFC methods for the chiral and achiral evaluation and purification of a variety of novel chemical entities across a range of operational scales from milligrams to hundreds of grams. This is an opportunity to apply your personal expertise in essential enabling technologies to advance efforts from initial drug design right through the API development process. Alongside this you will troubleshoot and provide first-line repairs to sophisticated analytical equipment and devise and oversee research projects to enhance our capabilities. The position requires an individual with strong analytical, technical, reporting and personal skills, experience of team or matrix management and a commitment to further personal development in both technical and leadership areas. This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: Chromatographic method development and purification of novel chemical entities. Management and development of the purification team. Investigation and implementation of novel technologies and improvements to methodologies to enhance capabilities. Engage in collaborative science efforts with affiliated team at the UP and Stevenage R&D hubs. Collaborate with key vendors to drive technology/capability strategy. Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: BSc in Chemistry with significant industrial experience and training, or MSc/PhD with demonstrable and practical industrial experience in a professional setting. Experience of contemporary analytical and purification chromatography platforms. Experience in the field of achiral and chiral separations using contemporary chromatographic methodologies. Experience with oligonucleotide/PROTAC/molecular glue/ADC analytical and purification challenges. Have leadership capabilities Preferred Qualifications: If you have the following characteristics, it would be a plus: Self-motivated with good organisational and leadership skills. Ability to work in a matrix environment to solve problems. Excellent written and oral communication skills. Background in associated analytical techniques such as mass spectrometry. Experience of developing and implementing novel technologies. Ability to perform both individually and as part of a team. Please include cover letter when applying for this jo #LI-GSK Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. 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