As a community, the University of Rochester is defined by a deep commitment to Meliora - Ever Better. Embedded in that ideal are the values we share: equity, leadership, integrity, openness, respect, and accountability. Together, we will set the highest standards for how we treat each other to ensure our community is welcoming to all and is a place where all can thrive. **Job Location (Full Address):** 601 Elmwood Ave, Rochester, New York, United States of America, 14642 **Opening:** Worker Subtype: Regular Time Type: Time as Reported / Per Diem Scheduled Weekly Hours: As Scheduled Department: 400133 Ophthalmology M&D Work Shift: UR - Day (United States of America) Range: UR URG 107 Compensation Range: $47,972.00 - $67,161.00 _The referenced pay range represents the minimum and maximum compensation for this job. Individual annual salaries/hourly rates will be set within the job's compensation range, and will be determined by considering factors including, but not limited to, market data, education, experience, qualifications, expertise of the individual, and internal equity considerations._ **Responsibilities:** Under general guidance and with latitude for exercising independent technical judgment, performs research related activities limited in scope and complexity in a specialized field. Provides direct research support and offers opportunity for future experimental and scientific development. This work will support the planning, design, and execution of experiments as well as direct studies. The Research Specialist will use existing protocols and will collaborate with other laboratories. Works independently with occasional input on modifying, varying or adapting standard laboratory procedures to meet special needs of research projects. Responsibilities POSITION SUMMARY: Technical Associate 1 will be the senior laboratory employee responsible for overseeing and conducting research in a Stem Cell and disease modeling lab at the University of Rochester Flaum Eye Institute. The primary focus of the research in the Singh laboratory is on investigating disease mechanisms and identifying rational therapies for specific retinal degenerative diseases. RESPONSIBILITIES: Technical Associate 1 will act as the Lab manager and will be responsible for performing experiments, analyzing data, helping with manuscript and grant preparation, overseeing other lab personnel, lab organization and ordering of supplies. The scientific research will be focused on utilizing animal models and human pluripotent stem cells (hPSC) to model and study retinal degenerative diseases. The suitable candidate should demonstrate the ability to carry out specific research projects independently under the guidance of the principal investigator (PI) and senior laboratory personnel (Staff Scientist/post doc). SPECIFIC RESPONSIBILITIES: - Independently conduct laboratory research projects under the guidance of the PI and senior laboratory personnel (Staff Scientist/post doc). - Perform cell and tissue culture daily and oversee the animal colony including genotyping the mice and conducting experiments as needed. The experimental techniques used will include tissue sectioning, immunohistochemistry, RNA and protein, RT and quantitative PCR, Western blotting, and immunoprecipitation. Other molecular and cell biology techniques may need to be utilized as dictated by the project. - Maintain laboratory, including ordering of reagents and supplies, preparing and projecting budgets, organizing and cleaning lab, maintaining and troubleshooting equipment, and training and supervising other laboratory personnel, including students and laboratory technicians. - Review current literature, analyze and summarize data, assist with manuscript and grant preparation, attend and present data at laboratory meetings. Also, work on various IRB and safety protocols and ensure that all the University guidelines and requirements are current and up to date - Create and modify standard operating procedures for techniques developed and used in the laboratory to ensure documentation and repeatability of lab protocols. - Other duties as necessary for completion of research project and work assigned by the PI. REQUIREMENTS: Well qualified candidates will have the following qualifications/ experience: Bachelor's degree is required, preferably with 3-4 years of experience in biological science research in a laboratory setting. Prior experience in animal handling and experiments as well as cell culture is preferred. Required computer skills include familiarity with MS Office. Experience with and knowledge of other statistical and image analysis software would be advantageous. Weekend work as deemed necessary for taking care of cells may be required. ] **EOE Minorities / Females / Protected Veterans / Disabled:** The University of Rochester is committed to fostering, cultivating, and preserving a culture of equity, diversity, and inclusion to advance the University’s mission to Learn, Discover, Heal, Create – and Make the World Ever Better. In support of our values and those of our society, the University is committed to not discriminating on the basis of age, color, disability, ethnicity, gender identity or expression, genetic information, marital status, military/veteran status, national origin, race, religion/creed, sex, sexual orientation, citizenship status, or any other status protected by law. This commitment extends to the administration of our policies, admissions, employment, access, and recruitment of candidates from underrepresented populations, veterans, and persons with disabilities consistent with these values and government contractor Affirmative Action obligations. Notice: If you are a **Current** **Employee,** please **log into myURHR** to search for and apply to jobs using the Jobs Hub. Your application, if submitted using this portal, cannot be moved forward. **Learn. Discover. Heal. Create.** Located in western New York, Rochester is our namesake and our home. One of the world’s leading research universities, Rochester has a long tradition of breaking boundaries—always pushing and questioning, learning and unlearning. We transform ideas into enterprises that create value and make the world ever better. If you’re looking for a career in higher education or health care, the University of Rochester may offer the perfect opportunity for your background and goals At the University of Rochester, we commit to diversity, equity, and inclusion and united by a strong commitment to be ever better—Meliora. It is an ideal that informs our shared mission to ensure all members of our community feel safe, respected, included, and valued.