A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

A Technical Development Principal Scientist position is available in  Biological Technologies- Analytical Development and Quality Control. 

The candidate will develop, optimize, and validate biochemical, immunochemical and cell-based assays for CMC technical development for clinical through launch-phase biologics products.  They will collaborate with multidisciplinary and cross functional teams to develop novel cell-based potency methods for products with complex mechanisms of action in support of process development, characterization, formulation screens, and GMP quality control of product release and stability.  The individual will be responsible for authoring test procedures, technical reports, regulatory filings and responses to Health Authority Q&A, and summarizing/presenting data and participating in group meetings and/or project teams. 

Additional responsibilities may include developing data analysis approaches, routine lab maintenance and equipment qualification, and supporting inspection readiness with other groups/sites.

Requirements:

PhD in Biological Sciences, an in-depth understanding of the fundamentals of cell biology and/or Immunology with a minimum of 5 years of industry experience is strongly preferred.

Hands-on experience in the development, performance, and troubleshooting of biochemical/immunochemical and cell-based assays to be used for functional characterization   

Demonstrate ability to work independently as well as with a team, handle multiple projects, demonstrate initiative, and adapt to fast-paced projects.

Must have strong attention to detail, effective verbal and written communication skills.

Relocation benefits are available for this job posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $119,600 to $222,000.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.