We’re seeking a Therapeutic Target Discovery Biologist to help us in our mission to revolutionize drug discovery through the use of breakthrough computational methods applied to drug design.

Our drug discovery group of over 80 scientists includes biologists, structural biologists, modelers, computational chemists, medicinal chemists, and crystallographers and software developers and engineers. Schrödinger has co-founded several biotech companies leading to exciting therapeutics and approaches, such as Nimbus (recent TYK2i acquisition by Takeda), Morphic Therapeutic (Phase 2 first-in-modality integrin inhibitor for IBD), and Structure Therapeutics (structure-based GPCR company). Four of the programs Schrödinger has worked on in the past seven years have progressed into the clinic and one has received FDA approval. 

As a member of our Therapeutics Group, you’ll bring your passion for identifying, reviewing and proposing therapeutic opportunities to address unmet medical needs. Your research experience in immune, cardiovascular, and/or metabolic disease biology and track record of goal-oriented, innovative and collaborative research, demonstrated through drug discovery project achievements or high impact peer-reviewed publications, will make you an asset in our efforts to champion target opportunities for Schrödinger’s growing pipeline.

Please submit a cover letter answering the following questions.

Which area of biology are you most interested in? What is something you learned recently about that topic?

Who will love this job:

A creative scientist who enjoys connecting basic biology to therapeutic opportunities to address unmet medical need A self-motivated professional who prefers a mix of independent and team work A polymath who’s interested in drug discovery, life sciences, and biotech An excellent verbal and written communicator and organizer (synthesizing information from disparate sources and articulating key insights is a crucial part of this role!) A collaborator who excels in a multidisciplinary and rapidly-changing atmosphere that includes strategizers, structural biologists, and chemists (this is not a lab-based position)

What you’ll do:

Conduct target analysis for new pipeline opportunities through multidisciplinary biology-driven approaches, including indication exploration, pathway mining, literature analysis, and human genetics Leverage data sources, platforms, and evidence vectors across orthogonal methods to generate compelling data packages to support target identification and analysis Perform target reviews to assess target validation, connection to disease pathophysiology, and mechanistic potential within an indication space Collaborate with subject matter experts in disease area biology, human genetics, structural biology, and competitive intelligence to position opportunities for Schrödinger’s pipeline Contribute to early stage drug discovery projects based on interest and skill fit

What you should have:

A PhD in biology, with three to five years of experience as a postdoc or in industry Subject matter expertise in cell or molecular biology, molecular genetics, biochemistry, or related life sciences field with research experience related to immune, cardiovascular and/or metabolic disease biology Pay and perks: Schrödinger understands it’s people that make a company great. Because of this, we’re prepared to offer a competitive salary, equity-based compensation, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have regular catered meals in the office, a company culture that is relaxed but engaged, and over a month of paid vacation time.  Our Office Management team also plans a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been included in Crain's New York Best Places to Work, BuiltIn's NYC Best Place to Work, and Newsweek's list of America's 100 Most Loved Workplaces.    Estimated base salary range: $115,000 - $160,000. Actual compensation package is dependent on a number of factors, including, for example, experience, education, degrees held, market data, and business needs. If you have any questions regarding the compensation for this role, do not hesitate to reach out to a member of our Strategic Growth team. 

Sound exciting? Apply today and join us!

As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.